Registration Dossier
Registration Dossier
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EC number: 212-595-6 | CAS number: 830-13-7
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 964
Materials and methods
- Principles of method if other than guideline:
- Method: other: Farbenfabrik Bayer AG
- GLP compliance:
- no
Test material
- Reference substance name:
- Cyclododecanone
- EC Number:
- 212-595-6
- EC Name:
- Cyclododecanone
- Cas Number:
- 830-13-7
- Molecular formula:
- C12H22O
- IUPAC Name:
- cyclododecanone
- Details on test material:
- Cyclododecanone of Hüls AG as produced in 1964, "chemically pure"
Constituent 1
Test animals
- Species:
- rat
- Sex:
- not specified
Administration / exposure
- Vehicle:
- other: acetone + vegetable oil (1:10)
- Details on dermal exposure:
- ADMINISTRATION:
- Volume administered or concentration: 2 ml/kg bw
- Duration of exposure:
- - Duration of exposure: 4 hours; removal with water & soap
- Doses:
- 500 mg/kg bw
- No. of animals per sex per dose:
- 5
- Details on study design:
- - Post dose observation period: 7 days
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 500 mg/kg bw
- Mortality:
- MORTALITY: none
- Clinical signs:
- other: CLINICAL SIGNS: none
Any other information on results incl. tables
Significant dermal resorption of the test substance was not observed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
