Registration Dossier
Registration Dossier
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EC number: 201-170-0 | CAS number: 79-03-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound propionyl chloride: no data
Hydrolysis product propionic acid (Ca propionate): With high probability acutely not harmful to aquatic algae after pH-adjustment
Hydrolysis product HCl: Acutely toxic to aquatic algae (pH-dependent)
Key value for chemical safety assessment
Additional information
Parent compound propionyl chloride:
No data are available for propionyl chloride (CAS 79-03-8). The substance rapidly decomposes in water and forms HCl (CAS 7647 -01 -0) and propionic acid (CAS 79 -09 -4). Therefore, the toxicity to algae is assessed on the basis of data on propionic acid and the structurally similar substance calcium propionate (CAS 4075-81-4).
In a test with green algae (Scenedesmus subspicatus), the 72-hr ErC50 (growth rate) was determined to be 48.7 mg/L [BASF AG, 1987]. In this study, the test solution was not buffered, resulting in low pH in the test solution. Aqueous solutions of calcium propionate do not display significant changes in pH and are therefore less toxic to aquatic organisms. For calcium propionate the 72-hr ErC50 for green algae (Scenedesmus subspicatus) is >500 mg/L [BASF AG, 1989]. The analogous substance was chosen in order to avoid the pH dependent effect of pure propionic acid solution. Hydrolysis product hydrochloric acid (HCl):The hydrolysis product hydrochloric acid (HCl) was tested in an algae growth inhibition test according to OECD 201 with Pseudokirchneriella subcapitata. The 72-h ErC50 was 0.492 mg/L (acid equivalent to pH 5.3), the 72-h NOEC was 0.097 (acid equivalent to pH 6; OECD, 2002).
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