Registration Dossier
Registration Dossier
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EC number: 907-873-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Acute oral toxicity: similar to OECD TG 401: LD50 >5000 mg/kg bw.
Acute dermal toxicity: similar to OECD TG 402: LD50 >5000 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 5 000 mg/kg bw
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 5 000 mg/kg bw
Additional information
Acute oral toxicity
In an acute oral toxicity study performed similar to OECD 401 (pre-OECD and pre-GLP), 10 rats were administered the test substance orally at a dose level of 5000 mg/kg bw. The animals were observed for mortality and clinical signs for 14 days. Three animals died during the study. Two animals died on day 1 and the third on day 6. Clinical signs included slow response and lethargy. The acute oral LD50 for the test substance in rats was determined to be >5000 mg/kg bw.
Acute dermal toxicity
In an acute dermal toxicity study performed similar to OECD 402 (pre-OECD and pre-GLP), 10 rabbits were administered the test substance orally at a dose level of 5000 mg/kg bw. The animals were observed for mortality and clinical signs for 14 days. No mortality was observed during the study and no clinical signs (such as irritation) were observed. The acute dermal LD50 for the test substance in rabbits was determined to be >5000 mg/kg bw.
Justification for classification or non-classification
The substance does not have to be classified for acute oral and acute dermal toxicity in accordance with EU CLP (EC 1272/2008 and its amendments).
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