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Diss Factsheets
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EC number: 240-015-1 | CAS number: 15879-01-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- Study well documented, meets generally accepted scientific principles, acceptable for assessment.
- Justification for type of information:
- Read across
Cross-reference
- Reason / purpose for cross-reference:
- read-across source
Reference
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- Test item concentration not in accordance to guideline.
- Justification for type of information:
- Read across
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: Continuous biological activated sludge treatment system
- Principles of method if other than guideline:
- Continuous biological activated sludge treatment system
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Name of test material (as cited in study report): Methyldiethanolamine (MDEA; CAS: 105-59-9)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): activated sludge from municipal wastewater treatment plant (TOC: 1920 mg/l, total solids (TS): 9.4 g/l)
- Parameter:
- % degradation (TOC removal)
- Value:
- > 91
- Sampling time:
- 21 d
- Details on results:
- - start-up period: ca. 2 weeks;
degradation for TOC of influent > 95 % - 80 ml/d MDEA (40 %): rise of TOC in effluent, increase of
degradation after 2 weeks - 40 ml/d MDEA (40 %): recovery after reduction of MDEA load; 95 % TOC degradation - MDEA-solution easily eliminated after adaption of the sludge: up to 96 % TOC-removal
- The continuous flow experiment showed a very good biodegradability of the wastewater including for high concentrations of MDEA solution with a TOC removal of 96%. - Conclusions:
- - very good biodegradability of the wastewater including for
high concentrations of MDEA-solution (TOC removal: 96 %)
- high biodegradation probably due to adaptation of
microorganisms
Data source
Reference
- Reference Type:
- publication
- Title:
- Biodegradation of triethanolamine.
- Author:
- West RJ and Gonsior SJ
- Year:
- 1 996
- Bibliographic source:
- Environ Toxicol Chem 15(4): 472-480.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: CO2 evolution test
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,2',2''-nitrilotriethanol
- EC Number:
- 203-049-8
- EC Name:
- 2,2',2''-nitrilotriethanol
- Cas Number:
- 102-71-6
- Molecular formula:
- C6H15NO3
- IUPAC Name:
- 2,2',2''-nitrilotriethanol
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): [14C]-triethanolamine
- Analytical purity: >= 98 %
- Specific activity (if radiolabelling): 17.61 mCi/mmol
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Mixed liquor activated sludge (secondary effluent)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): West Bay County WWTP, Bay City, Michigan, treating primarily municipal sewage up to 4 mio gallons per day
- Duration of test (contact time):
- 6 d
Initial test substance concentration
- Initial conc.:
- > 600 - < 5 500 µg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: minimal salts basal medium according to Stainer et al. (1966; J Gen Microbiol 43: 159-271)
- Additional substrate: no
- Solubilising agent (type and concentration if used): no
- Test temperature: 25 °C
- pH:
- pH adjusted: yes/no
- CEC (meq/100 g):
- Aeration of dilution water:
- Suspended solids concentration:
- Continuous darkness: yes
- Other:
TEST SYSTEM
- Culturing apparatus: 500-mL polypropylene Erlenmeyer flasks, sealed with rubber stoppers and fitted with CO2 traps
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions:
- Method used to create anaerobic conditions:
- Measuring equipment:
- Test performed in closed vessels due to significant volatility of test substance:
- Test performed in open system:
- Details of trap for CO2 and volatile organics if used: glass tubular CO2 traps (4 mL 1N KOH)
- Other: test material amended with 14C-TEA to yield 0.7 µCi/mL
SAMPLING
- Sampling frequency:
- Sampling method:
- Sterility check if applicable:
- Sample storage before analysis:
- Other:
CONTROL AND BLANK SYSTEM
- Inoculum blank:
- Abiotic sterile control: yes, via addition of formaldehyde (final concentration: 2.8%)
- Toxicity control:
- Other: performed in duplicate
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (test mat. analysis)
- Value:
- ca. 100
- Sampling time:
- 1 d
- Remarks on result:
- other: Primary biodegradation of 0.6 mg/l TEA in a test with 164 mg/l municipal activated sludge
- Parameter:
- % degradation (test mat. analysis)
- Value:
- ca. 100
- Sampling time:
- 5 d
- Remarks on result:
- other: Primary biodegradation of 0.6 mg/l TEA in a test with 164 mg/l municipal activated sludge
- Details on results:
- The rate constants in all test batches for degradation and mineralization are >0.359. According to GHS legislation, the substance is rapidly biodegradable. Therefore it can be assumed that the substance is also readily biodegradable.
Any other information on results incl. tables
Biodegradation (activated sludge):
Activated sludge (mg/L MLSS) |
Test item concentration (mg/L) |
Biodegradation rate constant (/d) |
Biodegradation half-life (d) |
CO2/ThCO2 (%) |
164 |
0.6 |
6.86 |
0.1 |
56+-10 |
164 |
5.7 |
1.36 |
0.51 |
54+-3 |
818 |
0.6 |
30 |
0.02 |
55+-1 |
818 |
5.7 |
6.7 |
0.01 |
52+-0 |
Mineralisation (activated sludge):
Activated sludge (mg/L MLSS) |
Test item concentration (mg/L) |
Mineralisation rate constant (/d) |
Mineralisation half-life (d) |
164 |
0.6 |
1.92 |
0.36 |
164 |
5.7 |
1.04 |
0.67 |
818 |
0.6 |
2.86 |
0.24 |
818 |
5.7 |
1.69 |
0.41 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: rapidly biodegradable according to GHS (readily biodegradability is therefore assumed)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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