2H-1,3-benzoxazine-2,4(3H)-dione

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2001

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2001

Report date:

2001

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

December 1992

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

July 27, 1995

Deviations:

no

GLP compliance:

yes

Type of method:

static method

Test material

Test material information

Constituent 1

Reference substance name:

1,3-benzoxazine-2,4-dione

Cas Number:

2037-95-8

IUPAC Name:

1,3-benzoxazine-2,4-dione

Results and discussion

Vapour pressure

Vapour pressure 1

Test no.:

#1

Temp.:

89.94 °C

Vapour pressure:

0.73 Pa

Vapour pressure 2

Test no.:

#2

Temp.:

98.93 °C

Vapour pressure:

0.85 Pa

Vapour pressure 3

Test no.:

#3

Temp.:

107.94 °C

Vapour pressure:

1.27 Pa

Any other information on results incl. tables

At the beginning of the test, the vapour pressure of the test substance decreased slightly every next measurement, due to the removal of volatile impurities. After measurement 123, this decrease became negligible and the vapour pressure was stable. So from that moment on, the collected data were used for the final result.

According to the guideline, the recommended range for the static method is 10 up to 100,000 Pa. However, in the paragraph Apparatus is stated that the static method can even be used at below 0.1 Pa whe using a capacitance manometer. As stated in the study protocol, the used apparatus is applicable >6 * 10 -3 Pa ( a capacitance manometer can be used in the pressure range from about 10 -5 to well above 105 Pa). The measured vapour pressures of V184844 were > 0.5 PA. All sensors, thermometers and pressure sensors heads are calibrated over the decades used in the experiments. Pressure sensor heads are calibrated from high vaccum (<<10 -5 Pa) to be seen as '0' value up to 1 Pa. Thermometers are calibrated in the measurement range used for testing.

Applicant's summary and conclusion

Conclusions:

The value of the vapour pressure of V184844 (CH02586) at 90, 100 and 110°C was determined to be:
p(90°c) = 0.70 +- 0.07 Pa
p(100°C) = 0.96 +- 0.07 Pa
p(110°C) = 1.29 +- 0.07 Pa