Boron, (benzenemethanamine)trifluoro-, (T-4)-, reaction products with Bu glycidyl ether

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Water solubility:

33.1 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

100 g/L

Incubation duration:

> 24 - < 72 h

Temp.:

20 °C

pH:

4.59

Details on results:

Prior to the preliminary test, a range of mixtures of test item and purified water (between 5 and 90% w/w) were prepared to visually assess the point at which saturation was reached. This visual assessment indicated that the solubility of the test item in water was less than 5% w/w.
On completion of the equilibration period, the three main test sample solutions were clear, colorless and contained undissolved test item. The solutions were decanted, centrifuged and filtered. Each filtrate was visually observed to be clear, colorless and free from undissolved test item. The presence of a Tyndall beam was checked but not observed.
It was noted that the analysis of the matrix blank solution produced some peaks, which represent less than 15% of the sample responses. The blank response was rejected from the calibration curve, since it had a detrimental effect on the fit of the trend line. However, it has to be noted that the matrix blank response affected equally the chromatography of the standards and the samples; therefore, it can be considered that its overall effect on the analysis results was negligible.
All individual water solubility results were within ± 15% of the mean, thus satisfying the criteria specified in the guidelines.

Conclusions:

The water solubility of Boron, (benzenemethanamine)trifluoro-,(t-4)-, reaction products with bu glycidyl ether has been determined to be 33.1 g/L of solution at 20.0 ± 0.5 °C, using a flask method designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Executive summary:

The water solubility of Boron, (benzenemethanamine)trifluoro-,(t-4)-, reaction products with bu glycidyl ether has been determined to be 33.1 g/L of solution at 20.0 ± 0.5 °C, using a flask method designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Description of key information

The water solubility of Boron, (benzenemethanamine)trifluoro-,(t-4)-, reaction products with bu glycidyl ether has been determined to be 33.1 g/L of solution at 20.0 ± 0.5 °C, using a flask method designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Key value for chemical safety assessment

Water solubility:

33.1 g/L

at the temperature of:

20 °C