Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation: in chemico
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Reference
Reference Type:
other:
Title:
Derek Nexus Prediction Report T2955
Author:
F.Linker
Year:
2018
Bibliographic source:
Lhasa Limited, Leeds
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Derek Nexus 2.2 (2018)
Version / remarks:
Derek KB 2018 1.1

In chemico test system

Details on the study design:
Smiles: CCC(C1=CC(=CC=C1)OC)(C(C)CN(C)C)O

Results and discussion

In vitro / in chemico

Results
Run / experiment:
other: Skin sensitisation in mammal is NON-SENSITISER (from KB: Derek KB 2018 1.1)

Applicant's summary and conclusion

Interpretation of results:
other: Skin sensitisation in mammal is NON-SENSITISER
Conclusions:
Skin sensitisation in mammal is NON-SENSITISER (from KB: Derek KB 2018 1.1)
Executive summary:

Skin sensitisation in mammal is NON-SENSITISER (from KB: Derek KB 2018 1.1)