Registration Dossier
Registration Dossier
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EC number: 276-650-6 | CAS number: 72403-67-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 972
- Report date:
- 1972
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The lethal doses (LD50) were determined according to the guidance of ROCHE / VI / Med., giving a 95% probability.
- GLP compliance:
- no
- Remarks:
- study pre-dates GLP.
Test material
- Reference substance name:
- 3(or 4)-(4-methylpenten-3-yl)cyclohex-3-ene-1-methyl acetate
- EC Number:
- 276-650-6
- EC Name:
- 3(or 4)-(4-methylpenten-3-yl)cyclohex-3-ene-1-methyl acetate
- Cas Number:
- 72403-67-9
- Molecular formula:
- C15H24O2
- IUPAC Name:
- [3-(4-methylpent-3-en-1-yl)cyclohex-3-en-1-yl]methyl acetate; [4-(4-methylpent-3-en-1-yl)cyclohex-3-en-1-yl]methyl acetate
- Details on test material:
- Giv. 81-0001 = Ro 81-0001 = Myraldyl Acetate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Füllinsdorf strain
- Sex:
- male/female
Administration / exposure
- No. of animals per sex per dose:
- 10 animals were used per dose and route of application, respectively.
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- >= 4 000 - <= 8 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: oral
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- From the results, it can be concluded that Myraldyl Acetate is practically not toxic.
Isolated cases of late death can be attributed, with regard to such high doses, to slowed resorption, what seems practically not relevant.
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