Registration Dossier
Registration Dossier
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EC number: 203-788-6 | CAS number: 110-65-6
Endpoint summary
Administrative data
Description of key information
Sensitisation (Humans): Conflicting results of unknown reliability
Additional information
There are a number of reports of allergic contact dermatitis in workers exposed to 1,4 -Butynediol (B3D) and, in some cases, these reports have been backed by the results of patch testing in effected individuals (ECB 2005). In experimental human patch testing with B3D, conflicting results have been reported (Kligman, 1966 and GAF, undated) and have not reliably demonstrated a skin sensitizing potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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