Registration Dossier
Registration Dossier
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EC number: 238-925-9 | CAS number: 14858-73-2
Carcinogenicity
Administrative data
Description of key information
No carcinogenicity study is required.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The available data give no concern on carcinogenic properties of the test substance. Thus, classification of Bis-(2-ethylhexyl)carbonate as carcinogenic is not required according to Directive 67/548/EEC as well as GHS Regulation EC No 1272/2008 and therefore labelling is not necessary.
Additional information
No carcinogenicity study is required. The mutagenic and clastogenic potential of Bis(2-ethylhexyl) carbonate has been evaluated in the full range of in vitro studies and in a single in vivo genotoxicity study. There was no evidence for genotoxic properties of Bis(2-ethylhexyl) carbonate. Available data on repeated dose toxicity give no concern on carcinogenic properties of the substance. Although carcinogenicity studies are not available for Bis(2-ethylhexyl) carbonate, available data on genotoxicity and repeated dose toxicity do not raise any specific concerns with regard to carcinogenicity.
Carcinogenicity in humans is not expected.
Justification for selection of carcinogenicity via oral route endpoint:
No carcinogenicity study is required.. Available data give no concern on carcinogenic properties of the substance.
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