Substance Information
Substance Information
New Data Availability System
A new Data Availability System is being developed by ECHA. To begin with this system will take over the responsibility of making REACH registration data available, once it is ready. We expect the first version to be publicly available by the end of 2023.
Since ECHA aims to devote our maximum effort to this new system, we can no longer maintain REACH registration data on the current Dissemination Platform. As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. The factsheets will remain online, but will not be updated.
As a consequence, REACH registration data will likewise not be updated in Infocards, Brief Profiles, the Advanced search, or the Nanomaterials on the EU market portal. We will inform you of what you can expect in the new system, along with details of when and where to find it.
We appreciate your understanding in the meantime.
1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol
EC / List no.: 701-173-1
CAS no.: -
Mol. formula:
Danger! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye irritation, is harmful if inhaled, is suspected of causing cancer, may cause damage to organs through prolonged or repeated exposure, causes skin irritation, may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled and may cause respiratory irritation.
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A majority of data submitters agree this substance is Skin sensitising |
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A majority of data submitters agree this substance is Respiratory sensitising |
This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.
This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
This substance is used in the following products:
adhesives and sealants and
coating products.
Other release to the environment of this substance is likely to occur from:
indoor use and
outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).
Article service life
Other release to the environment of this substance is likely to occur from:
outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and
indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
This substance can be found in products with material based on:
plastic (e.g. food packaging and storage, toys, mobile phones).
Widespread uses by professional workers
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
ECHA has no public registered data on the types of manufacture using this substance.
Other release to the environment of this substance is likely to occur from:
indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and
outdoor use.
Formulation or re-packing
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
Release to the environment of this substance can occur from industrial use:
formulation of mixtures.
Uses at industrial sites
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
ECHA has no public registered data on the types of manufacture using this substance.
Release to the environment of this substance can occur from industrial use:
for thermoplastic manufacture,
in processing aids at industrial sites,
in the production of articles and
as an intermediate step in further manufacturing of another substance (use of intermediates).
Manufacture
Release to the environment of this substance can occur from industrial use:
manufacturing of the substance.
The InfoCard summarises the non-confidential data on substances as held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The InfoCard is automatically generated. Information requirements under different legislative frameworks may therefore not be up–to–date or complete. Substance manufacturers and importers are responsible for consulting official publications. This InfoCard is covered by the ECHA Legal Disclaimer.
about INFOCARD - Last updated: 18/02/2023