Registration Dossier
Registration Dossier
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EC number: 223-051-2 | CAS number: 3709-43-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- RTECS Number : DB6833400
- Year:
- 2 012
- Bibliographic source:
- RTECS;HPV384 U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Stilbene Fluorescent Brighteners .pdf http://www.epa.gov/HPV/pubs/summaries/stilbnint/c16114tc.htm Volume(issue)/page/year: -,-,2005
- Reference Type:
- other: Authoritative data base
- Title:
- GCID 221778
- Year:
- 2 011
- Bibliographic source:
- ACToR (Aggregated Computational Toxicology Resource);Data extracted from the robust summary received by CBIC January 9, 2006 and posted to the HPV Challenge Program website February 8, 2006.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from RTECS
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Disodium 4,4'-dinitrostilbene-2,2'-disulphonate
- EC Number:
- 223-051-2
- EC Name:
- Disodium 4,4'-dinitrostilbene-2,2'-disulphonate
- Cas Number:
- 3709-43-1
- Molecular formula:
- C14H10N2O10S2.2Na
- IUPAC Name:
- disodium 4,4'-dinitrostilbene-2,2'-disulphonate
- Details on test material:
- - Name of test material (as cited in study report): disodium 4,4'-dinitrostilbene-2,2'-disulphonate
- Substance type: Organic
- Physical state: Solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 16 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value
- Mortality:
- 50 percent kill
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Details of toxic effects not reported other than lethal dose value which is >16000 mg/kg by using standard acute method.
- Executive summary:
LD50 oral value for disodium 4,4'-dinitrostilbene-2,2'-disulphonate is >16000 mg/kg by standard acute method. This value suggests that it is not toxic via oral route.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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