methyl 2-hydroxybut-3-enoate

Guidance on Safe Use

First-aid measures

Description of first aid measures:

• Inhalation: Remove person to fresh air and keep comfortable for breathing. Call a physician or poison control centre immediately.


• Skin contact: Take off immediately all contaminated clothing and wash it before reuse. Wash off immediately with plenty of water. Call a physician or poison control centre immediately.


• Eye contact: Immediately flush eye(s) with plenty of water. Take victim immediately to hospital. Continue rinsing eyes during transport to hospital. Remove contact lenses, if present and easy to do. Continue rinsing.


• Ingestion: Rinse mouth with water. Do NOT induce vomiting. Call a POISON CENTER /doctor.

 

Most important symptoms and effects:

• Inhalation: Inhalation of vapours may cause mild irritation to the mucous membrane. May cause respiratory irritation.


• Skin contact: Causes skin burns. May cause an allergic skin reaction.


• Eye contact: Causes serious eye damage.


• Ingestion: Harmful if swallowed. Ingestion may cause irritation to mucous membranes.

Fire-fighting measures

Combustible liquid.

 

Suitable extinguishing media: Product is compatible with standard fire-fighting agents.

Special hazards arising from the substance or mixture: No hazards to be specially mentioned

Advice for firefighters: Wear full protective clothing and self-contained breathing apparatus. Do not allow run-off from fire fighting to enter drains or water courses.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:

• Avoid breathing mist or vapours.


• Avoid contact with skin, eyes and clothing.


• Use personal protective equipment.


• Follow safe handling advice and personal protective equipment recommendations.

 

Environmental precautions:

• Do not flush into surface water or sanitary sewer system.


• Try to prevent the material from entering drains or water courses.


• Local authorities should be advised if significant spillages cannot be contained.

 

Methods and materials for containment and cleaning up:

• Dispose of as hazardous waste in compliance with local and national regulations.


• Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations.


• Never soak up spilled or leaked acids and bases with sawdust, wood chips or similar materials.


• Pick up and transfer to properly labelled containers.

Handling and storage

Precautions for safe handling:

• Avoid contact with eyes.


• Use only in an area equipped with a safety shower.


• Avoid inhalation of vapour or mist.


• Avoid contact with skin, eyes and clothing.


• Do not eat, drink or smoke when using this product.


• Handle in accordance with good industrial hygiene and safety practice.


• Persons with a history of skin sensitisation problems or asthma, allergies, chronic or recurrent respiratory disease should not be employed in any process in which this mixture is being used.


• Wear personal protective equipment.

 

Conditions for safe storage, including any incompatibilities

• Keep in properly labelled containers.


• Keep container closed when not in use.


• Keep cool.


• Protect from sunlight.


• Store contents under inert gas.


• Keep in a well-ventilated place.

 

Further information on storage conditions:

• Keep away from direct sunlight.

 

Specific end use

• For R&D use only. Not for pharmaceutical, household or other uses.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

1760

Shipping information

Proper shipping name and description:

Corrosive liquid, n.o.s.

Chemical name:

Methyl DL-2-Hydroxy-3-butenoate

Language:

English

Class or division:

Class 8: Corrosive substances

Subsidiary hazard(s):

Class 8: Corrosive substances

Packing group:

Packing group III: Substances presenting low danger

Labels:

ADR/RID: Class: 8; Labels: 8
IMDG: Class: 8; Labels: 8
IATA: Class: 8; Labels: 8
49 CFR: Class: 8; Labels: 8

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Control parameters

Exposure Limit Values:

Exposure limits may vary. It is recommended that information about locally applicable exposure limits is obtained.

Components	Exposure Limit Values		Source
Methanol (67-56-1)
	TWA	200 ppm / 266 mg/m³	EH40 (2011:12)
	STEL	250 ppm / 333 mg/m³	EH40 (2011:12)

DNEL/PNEC

Methanol (67-56-1)

Workers	DNEL	No data available
Environment	PNEC	No data available

Exposure controls

Individual protection measures, such as personal protective equipment:

Eye/face protection: Safety goggles

Skin protection: 

• Hand protection: Wear protective gloves. Glove material: PVC


• Body Protection: Full protective suit Rubber apron Safety shoes recommended when handling heavy containers.


• Respiratory protection: Wear respiratory protection. Respirator with combination filter for vapour/particulate (EN 141)


• Other protection: Wash hands thoroughly after handling. Contaminated work clothing should not be allowed out of the workplace. Change working clothes after each workshift. Wash contaminated clothing before reuse.

Stability and reactivity

Reactivity: Stable under normal conditions.

Chemical stability: Decomposes upon contact with air.

Possibility of hazardous reactions: No dangerous reaction known under conditions of normal use.

Conditions to avoid: Exposure to air. Strong sunlight for prolonged periods.

Incompatible materials: Oxidizing agents

Hazardous decomposition products: Prolonged storage of the product can cause the stabiliser to lose its effectiveness.

Disposal considerations

Waste treatment methods: Dispose of as hazardous waste in compliance with local and national regulations.