Registration Dossier
Registration Dossier
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EC number: 222-872-3 | CAS number: 3644-12-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 978
- Report date:
- 1978
Materials and methods
Test guideline
- Guideline:
- other: "Appraisal of the safety of chemicals in foods, drugs and cosmetics", by the staff of the Division of Pharmacology, FDA, 1959
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- N-(methoxymethyl)methacrylamide
- EC Number:
- 222-872-3
- EC Name:
- N-(methoxymethyl)methacrylamide
- Cas Number:
- 3644-12-0
- Molecular formula:
- C6H11NO2
- IUPAC Name:
- N-(methoxymethyl)-2-methylacrylamide
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 1 620 mL/kg bw
- Based on:
- test mat.
- 95% CL:
- 1 500 - 1 740
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
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