Registration Dossier
Registration Dossier
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EC number: 205-471-8 | CAS number: 141-23-1
Endpoint summary
Administrative data
Description of key information
Sensitising in some human case reports
Additional information
In a study of 32 human volunteers in a maximization repeated-insult patch test to ethyl ricinoleate, no signs of irritation or sensitisation were reported. While there have been several accounts of dermal sensitisation in humans exposed to 12 -hydroxystearate compounds, including one case of a military occupational contact allergy to the rubber mask of a respirator, these do not override the negative findings of the human HRIPT or the animal sensitisation testing. Taken as a weight of evidence, the substance is not considered a dermal sensitiser.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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