2-Propenoic acid, 2-fluoro-, methyl ester

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.006 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.061 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.001 mg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

10 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

no exposure of sediment expected

Sediment (marine water)

Hazard assessment conclusion:

no exposure of sediment expected

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

no exposure of soil expected

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

Toxicity studies in fish, invertebrates and algae have been conducted for 2-propenoic acid, 2-fluoro, methyl ester and it was concluded that fish are the most sensitive organisms based on the available studies. A reliable short-term toxicity study with fish is available for 2-propenoic acid, 2-fluoro, methyl ester with a 96-hour LC50 of 6.1 mg/L. This value is the basis for the freshwater PNEC with an assessment factor of 1000 applied to account for potential intra- and interspecific variation, the use of short-term aquatic data and other general uncertainties, such as laboratory to field extrapolation. The microbial study is waived due to significant losses of test substance due to volatilisation under the test conditions making it not technically feasible to conduct this study.

In accordance with Annex X of the Regulation (EC) No 1907/2006 REACH concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), information regarding long-term sediment and soil toxicity tests need not be conducted unless the chemical safety assessment indicates the need to further assess the effects of the substance to these organisms. The substances low potential to adsorb or partition to soil and sediment is demonstrated by the low Koc (<1.25) and very low log octanol-water partition coefficient (Log Kow) of 0.931. In addition, the substance is likely to undergo rapid abiotic degradation and some biodegradation. It is concluded that direct or indirect exposure of sediments and soils is unlikely and further testing is not required.

Conclusion on classification

2 -Propenoic acid, 2-fluoro, methyl ester is not classified as a persistent, bioaccumulative or toxic (PBT) substance. Based on available reliable data for toxicity of 2-propenoic acid, 2-fluoro, methyl ester, short-term acute toxicity (LC50 or EC50) to aquatic organisms is >0.01 mg/L and does not meet the definitive toxicity criterion according to the ECHA guidance on PBT assessment (Part C). Therefore, it is concluded that the substance does not fulfill the toxicity (T) criterion as laid down in Annex XIII of Regulation (EC) No 1907/2006.

Based on a reliable hydrolysis study, 2-propenoic acid, 2-fluoro, methyl ester does not meet the criteria for Persistence (P) as the half-life is < 40 days in freshwater. The measured Log Kow is less than 4.5 and it is concluded that there is a low potential for exposure and bioaccumulation in aquatic and terrestrial organisms. 2-propenoic acid, 2-fluoro, methyl ester does not fulfill the criteria “bioaccumulative (B)” or “very bioaccumulative (vB)”. The overall conclusion is that 2-propenoic acid, 2-fluoro, methyl ester, is not considered a PBT or vPvB substance. No further testing is required.