Registration Dossier
Registration Dossier
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EC number: 226-364-2 | CAS number: 5372-81-6
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2009
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Guideline:
- other: Visual testing of solubiity after shaking the test substance in the solvent at room temperature
- Deviations:
- not applicable
- Principles of method if other than guideline:
- Visual testing of solubiity after shaking the test substance in the solvent at room temperature
Documentation No 4063 - GLP compliance:
- not specified
Test material
- Reference substance name:
- Dimethyl 2-aminoterephthalate
- EC Number:
- 226-364-2
- EC Name:
- Dimethyl 2-aminoterephthalate
- Cas Number:
- 5372-81-6
- Molecular formula:
- C10H11NO4
- IUPAC Name:
- 1,4-dimethyl 2-aminobenzene-1,4-dicarboxylate
- Reference substance name:
- dimethyl-2-aminoterephthalate
- IUPAC Name:
- dimethyl-2-aminoterephthalate
- Details on test material:
- grey powder
purity: 99.52 %
Constituent 1
Constituent 2
Results and discussion
Solubility in organic solvents / fat solubilityopen allclose all
- Medium:
- DMSO
- Solubility:
- > 1 g/L
- Temp.:
- 23 °C
- Medium:
- n-octanol
- Solubility:
- > 1 g/L
- Temp.:
- 23 °C
- Test substance stable:
- yes
- Details on results:
- Stability:
The test substance is stable and homogeneous for more than 72 hours in DMSO (0.1 and 50 mg/ml) and in ethanol (0.1 and 50 mg/ml) at room temperatuie.
Analytical method: HPLC
Apparatus: Aligent 1100 Series
Remark: Intensive stirring is necessary
Applicant's summary and conclusion
- Conclusions:
- The estimated solubility of the test item in DMSO and n-Octanol is > 1 g/L.
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