Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 288-922-1 | CAS number: 85940-32-5 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Elettaria cardamomum, Zingiberaceae.
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Remarks:
- Classification based on calculation rules for mixtures of the CLP Regulation
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Data source
Reference
- Reference Type:
- other: Guidance
- Title:
- Guidance on the Application of the CLP Criteria - Guidance to Regulation (EC) No 1272/2008 on classification, labelling and packaging (CLP) of substances and mixtures
- Author:
- ECHA
- Year:
- 2 017
- Bibliographic source:
- ECHA-17-G-21-EN
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- Classification based on calculation rules for mixtures of the CLP Regulation
Test material
- Reference substance name:
- Cardamom, ext.
- EC Number:
- 288-922-1
- EC Name:
- Cardamom, ext.
- Cas Number:
- 85940-32-5
- Molecular formula:
- Not applicable, UVCB
- IUPAC Name:
- 1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane; 2-(4-methylcyclohex-3-en-1-yl)propan-2-yl acetate
- Test material form:
- not specified
- Details on test material:
- - Name of test material (as cited in study report): Cardamom oil
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- other: classification
- Remarks on result:
- other: skin irritant category 2
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritant) based on GHS criteria
- Conclusions:
- The registered substance has more than 10% of its constituents classified as Skin irritant Category 2 and should be classified as a skin irritant without further testing according to the rules for classification of mixtures of Regulation (EC) No 1272/2008.
- Executive summary:
The NCS is composed of several identified constituents and in that, it can be considered as a mixture according to the definition of the CLP Regulation.
The decision logic for classification of mixtures from the ECHA Guidance on the Application of the CLP Criteria (2017) was used to determine the skin irritation/corrosion hazard of the registered substance. The decision of classification as skin irritant was based on existing data on constituents (additivity principles): the registered substance has more than 10% of its constituents classified as Skin irritant Category 2 and should be classified as a skin irritant without further testing according to the rules for classification of mixtures of Regulation (EC) No 1272/2008.
Constituent CAS Classification Source Linalyl acetate 115-95-7 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/14484 Limonene 138-86-3 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/24067 Linalool 78-70-6 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/14501/1 Beta-myrcene 123-35-3 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/14795 Terpineol multiconstituent 8000-41-7 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/16031/2/1 Geranyl acetate 105-87-3 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/5962 Terpineol-4 562-74-3 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/21354 Alpha pinene 80-56-8 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/14724 Geraniol 106-24-1 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/14184 Geranial 141-27-5 H315 ECHA C&L inventory - self classification: https://echa.europa.eu/fr/registration-dossier/-/registered-dossier/17552 Source: ECHA disseminated dossiers or self classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
