Tidligere/resultat
Tidligere/resultat
Tidligere/resultat
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Bis(2-butoxyethyl) adipate | 205-466-0 | 141-18-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Bis(2-chloroethoxy)methane | 203-920-2 | 111-91-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 |
Details | |
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane | 940-783-4 | - |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 ) |
02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 |
Details | |
Bis(2-chloroethyl) 3,3'-[(2,5-dimethyl-p-phenylene)bis[iminocarbonyl(2-hydroxy-1,3-naphthylene)azo]]di-p-toluate | 269-507-4 | 68259-05-2 | Sub-chronic toxicity (90 day): inhalation || Note: Testing proposal is based on concern identified by the registrant | 24/07/2019 | 09/09/2019 | Details | |
bis(2-dimethylaminoethyl)(methyl)amine | 221-201-1 | 3030-47-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/03/2014 03/03/2014 |
17/04/2014 17/04/2014 |
Details | |
Bis(2-ethylhexyl) adipate | 203-090-1 | 103-23-1 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 |
Details | |
Bis(2-ethylhexyl) fumarate | 205-448-2 | 141-02-6 |
Bioaccumulation aquatic / sediment Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
14/02/2011 14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 31/03/2011 |
Details | |
Bis(2-ethylhexyl) peroxydicarbonate | 240-282-4 | 16111-62-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
Bis(2-ethylhexyl) tetrabromophthalate | 247-426-5 | 26040-51-7 | Reproductive toxicity (pre-natal developmental toxicity) | 16/05/2014 | 30/06/2014 | Details | |
bis(3,5,5-trimethylhexanoyl) peroxide | 223-356-0 | 3851-87-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
bis(4-(1,1,3,3-tetramethylbutyl)phenyl)amine | 239-816-9 | 15721-78-5 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 |
Details | |
Bis(4-chlorophenyl) sulphone | 201-247-9 | 80-07-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
bis(4-chlorophenyl) sulphone | 201-247-9 | 80-07-9 |
Bioaccumulation: terrestrial Reproductive toxicity (pre-natal developmental toxicity) |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
Bis(4-methylbenzoyl)peroxide | 407-950-9 | 895-85-2 | 6.1.2 Long-term toxicity to fish||Note: testing proposed with p-toluic acid (EC no. 202-803-3) or with bis(4-methylbenzoyl) peroxide (EC no. 407-905-9) | 08/03/2024 | 22/04/2024 | Details | |
bis(4-tert-butylcyclohexyl) peroxydicarbonate | 239-557-1 | 15520-11-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
Bis(dibutyldithiocarbamato-S,S')copper | 237-695-7 | 13927-71-4 | Long-term toxicity to fish | 22/06/2017 | 07/08/2017 | Details | |
Bis(nonylphenyl)amine / Reaction products of Benzeneamine, N-phenyl- with nonene (branched) | - | - |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
28/02/2011 28/02/2011 |
14/04/2011 14/04/2011 |
Details | |
Bis(O,O-diisopropyl dithiophosphate)bis(cyclohexylamine) zinc | 809-986-4 | 52585-16-7 | Genetic toxicity in vivo | 22/04/2021 | 07/06/2021 | Details | |
bis(piperidinothiocarbonyl) hexasulphide | 213-537-2 | 971-15-3 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 16/02/2015 | 02/04/2015 | Details | |
bis(piperidinothiocarbonyl) hexasulphide | 213-537-2 | 971-15-3 | Reproductive toxicity (pre-natal developmental toxicity) | 29/04/2014 | 13/06/2014 | Details | |
Bis(triethoxysilylpropyl)amine | 236-818-1 | 13497-18-2 | Sub-chronic toxicity (90-day): oral | 22/09/2022 | 07/11/2022 | Details | |
Bis(triethoxysilylpropyl)amine | 236-818-1 | 13497-18-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Bis(trimethoxysilylpropyl)amine (EC 403-480-3) || Note: Testing proposal is based on concern identified by the registrant | 07/07/2020 | 21/08/2020 | Details | |
Bis(trimethoxysilylpropyl)amine | 280-084-5 | 82985-35-1 |
Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 |
Details | |
bis(α,α-dimethylbenzyl) peroxide | 201-279-3 | 80-43-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 |
Details | |
Bis(α,α-dimethylbenzyl) peroxide | 201-279-3 | 80-43-3 | Reproductive toxicity (pre-natal developmental toxicity | 20/10/2016 | 05/12/2016 | Details | |
bis(α,α-dimethylbenzyl) peroxide | 201-279-3 | 80-43-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 10/05/2022 | 27/06/2022 | Details | |
bis(α,α-dimethylbenzyl) peroxide | 201-279-3 | 80-43-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 16/12/2020 | 01/02/2021 | Details | |
Bis[2-[2-(1-methylethyl)-3-oxazolidinyl]ethyl] hexan-1,2-diylbiscarbamate | 261-879-6 | 59719-67-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
Bis[2-[2-(1-methylethyl)-3-oxazolidinyl]ethyl] hexan-1,2-diylbiscarbamate | 261-879-6 | 59719-67-4 | Genetic toxicity in vivo | 01/07/2021 | 16/08/2021 | Details | |
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate | 940-272-6 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 16/10/2017 |
Details | |
Bisdecanoyl peroxide | 212-092-1 | 762-12-9 | Long-term toxicity to fish | 27/09/2017 | 13/11/2017 | Details | |
Bisisobutyryl peroxide | 222-340-0 | 3437-84-1 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
04/04/2014 04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 19/05/2014 |
Details | |
Bisisopropyl peroxydicarbonate | 203-317-4 | 105-64-6 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 24/08/2020 | 08/10/2020 | Details | |
Bismuth | 231-177-4 | 7440-69-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
bismuth citrate | 212-390-1 | 813-93-4 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4) Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8, CAS 1304-85-4) |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
bismuth hydroxide nitrate oxide | 215-136-8 | 1304-85-4 | Sub-chronic toxicity (90-day): oral | 18/09/2014 | 03/11/2014 | Details | |
bismuth oxide salicylate | 238-953-1 | 14882-18-9 | Sub-chronic toxicity (90 day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8) | 18/09/2014 | 03/11/2014 | Details | |
Bismuth trinitrate | 233-791-8 | 10361-44-1 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8) Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8) |
20/09/2013 20/09/2013 |
04/11/2013 04/11/2013 |
Details | |
Boric acid (H3BO3), reaction products with ethanolamine | 302-207-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/01/2012 16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 01/03/2012 |
Details | |
Boron trifluoride | 231-569-5 | - | Genetic toxicity in vivo | 01/07/2011 | 15/08/2011 | Details | |
Boron, (benzenemethanamine)trifluoro-, (T-4)-, reaction products with Bu glycidyl ether | 270-821-9 | 68478-46-6 | Genetic toxicity in vivo | 03/05/2023 | 19/06/2023 | Details | |
Branched hexatriacontane | 417-070-7 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) |
26/08/2021 26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 11/10/2021 |
Details | |
branched-nonyl 3,5,5 trimethylhexanoate | 701-133-3 | - | Sub-chronic toxicity (90-day): oral || Note: previous EC no 609-993-0 | 21/05/2018 | 05/07/2018 | Details | |
Bumetrizole | 223-445-4 | 3896-11-5 | Bioaccumulation aquatic / sediment | 18/06/2018 | 02/08/2018 | Details | |
But-1-ene | 203-449-2 | 106-98-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
But-1-ene | 203-449-2 | 106-98-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Sub-chronic toxicity (90 day): inhalation
|| Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
butan-2-one O,O',O''-(vinylsilylidyne)trioxime | 218-747-8 | 2224-33-1 |
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9). |
25/06/2015 | 10/08/2015 | Details | |
Butane-1,4-diol | 203-786-5 | 110-63-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/04/2021 | 07/06/2021 | Details | |
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts | 939-691-7 | - | Reproductive toxicity (pre-natal developmental toxicity) | 17/09/2019 | 01/11/2019 | Details | |
Butene | 246-689-3 | 25167-67-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with 2-methylpropene (EC no. 204-066-3) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |