Registered substances
Registered substances
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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More
Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.
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Registered Substances Factsheets
Substances which have been registered and can be placed on the EEA market by those companies with a valid registration
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Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
---|---|---|---|---|---|---|---|---|
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-Propanesulfonamide, N-[3-[(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]- | 806-749-7 | 918504-27-5 | - | View substance registered dossier |
Roche Ireland Limited | Clarehill . Clarecastle Ireland | Ireland | Active | 1-Propanesulfonamide, N-[3-[(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]- | 806-749-7 | 918504-27-5 | 2020; 2021 | View substance registered dossier |
Roche Ireland Limited | Clarehill . Clarecastle Ireland | Ireland | Active | 1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- | 806-756-5 | 1262985-24-9 | 2020; 2021 | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- | 806-756-5 | 1262985-24-9 | - | View substance registered dossier |
Sigma-Aldrich Chemie GmbH | Riedstrasse 2 89555 Steinheim Germany | Germany | Active | 1-Propanesulfonic acid, 3-(cyclohexylamino)-2-hydroxy-, monosodium salt | 700-631-8 | 102601-34-3 | - | View substance registered dossier |
Roche Diagnostics GmbH | Sandhoferstrasse 116 68305 Mannheim Germany | Germany | Active | 1-Propanesulfonic acid, 3-(cyclohexylamino)-2-hydroxy-, monosodium salt | 700-631-8 | 102601-34-3 | - | View substance registered dossier |
SIGMA-ALDRICH CHEMIE GMBH | Riedstrasse 2 89555 Steinheim Germany | Germany | Active | 1-Propanesulfonic acid, 3-(cyclohexylamino)-2-hydroxy-, monosodium salt | 700-631-8 | 102601-34-3 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | 1-Propanesulfonic acid, 3-[hexyl[(nonafluorobutyl)sulfonyl]amino]-2-hydroxy-, Monoammonium Salt | 468-470-3 | - | - | View substance registered dossier |
RECORDATI SPA | Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy | Italy | Active | 1-Propanone, 1-[2-(2-propen-1-yloxy)phenyl]- | 604-312-3 | 142819-94-1 | - | View substance registered dossier |
Evonik Operations GmbH | Rellinghauser Straße 1-11 45128 Essen Germany | Germany | Active | 1-Propanone, 2-hydroxy-2-methyl-, 1-(4-C10-13-alkylphenyl) derivs. | 600-033-6 | 1001416-18-7 | - | View substance registered dossier |
IGM Resins B.V. | Gompenstraat 49 5145 RA Waalwijk Netherlands | Netherlands | Active | 1-Propanone, 2-hydroxy-2-methyl-, 1-(4-C10-13-alkylphenyl) derivs. | 600-033-6 | 1001416-18-7 | - | View substance registered dossier |
Első Vegyi Industria ZRt. | Kartács utca 6. H-1139 BUDAPEST Hungary | Hungary | Active | 1-Propanone, 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, hydrochloride (1:1) | 609-494-8 | 37951-53-4 | 2018 | View substance registered dossier |
Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Active | 1-Propen-1,2,3-tricarbonsäure tris(2-(2,2,3,3,3,4,4,4-heptafluorbutoxy)-1-(methyl)-ethyl)ester | 943-789-5 | 1449567-31-0 | - | View substance registered dossier |
Dyneon GmbH | Industrieparkstrasse 1 84508 Burgkirchen a. d. Alz Germany | Germany | Active | 1-Propene, 1,1,2,3,3-pentafluoro-3-(1,1,2,2,3,3,3-heptafluoropropoxy)- | 817-766-4 | 91891-42-8 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | 1-Propene, 2-methyl-, chlorinated, epoxidized, distn. residues | 304-801-9 | 94279-55-7 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | 1-Propene, chlorinated, epoxidized, distn. residues | 304-800-3 | 94279-54-6 | - | View substance registered dossier |
INEOS Derivatives Lavera SAS (Oxide) | Avenue de la bienfaisance BP6 133117 Lavera France | France | Active | 1-Propene, hydroformulation products, by-products from, distillation residues | 606-535-1 | 203588-70-9 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | 1-Propene, hydroformylation products, high-boiling | 271-363-2 | 68551-11-1 | - | View substance registered dossier |
3M Belgium BVBA/SPRL (OR8) | Hermeslaan 7 1831 Diegem Belgium | Belgium | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | - | View substance registered dossier |
PPG Europe B.V. - OR1 | Amsterdamseweg 14 1422 AD Uithoorn Netherlands | Netherlands | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | 2021 | View substance registered dossier |
Resonac Europe GmbH (IMP) | Daimlerstrasse 19 86368 Gersthofen Germany | Germany | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | - | View substance registered dossier |
PPG Europe B.V. - OR2 | Amsterdamseweg 14 1422 AD Uithoorn Netherlands | Netherlands | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | 2021 | View substance registered dossier |
PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc. | Via Serra, 1 15028 Quattordio Italy | Italy | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | - | View substance registered dossier |
Lyondell Chemie Nederland B.V. | Deltseplein 27E 3013 AA Rotterdam Netherlands | Netherlands | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | 2016 | View substance registered dossier |
Henkel Global Supply Chain B.V. | Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands | Netherlands | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | 2022 | View substance registered dossier |
Monument Chemical | Haven 1972 Ketenislaan 3 9130 Kallo Belgium | Belgium | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | - | View substance registered dossier |
Huntsman Advanced Materials (Europe) BV OR-USA | Everslaan 45 B-3078 Everberg Belgium | Belgium | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | 2021 | View substance registered dossier |
PPG Europe B.V. - OR3 | Amsterdamseweg 14 1422 AD Uithoorn Netherlands | Netherlands | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | 2021 | View substance registered dossier |
Monument Chemical_ORKY | Haven 1972 Ketenislaan 3 9130 Kallo Belgium | Belgium | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | - | View substance registered dossier |
DOW BENELUX B.V. - OR2 | Postbus 48 4530 AA Terneuzen Netherlands | Netherlands | Active | 1-propoxypropan-2-ol | 216-372-4 | 1569-01-3 | 2014 | View substance registered dossier |
Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Active | 1-propyl-4-[(trans,trans)-4'-propyl[1,1'-bicyclohexyl]-4-yl]-benzene | 617-607-7 | 84656-77-9 | 2021 | View substance registered dossier |
[Confidential] | - | - | - | 1-propylbutylamine | 240-814-5 | 16751-59-0 | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-Pyrrolidinecarboxylic acid, 2,2'-[[(6S)-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]di-1H-imidazole-5,2-diyl]bis-, 1,1'-bis(1,1-dimethylethyl) ester, (2S,2'S)- | 813-165-6 | 1369595-05-0 | - | View substance registered dossier |
ACS DOBFAR S.p.A | Viale Addetta 4/12 20067 Tribiano Milano Italy | Italy | Active | 1-Pyrrolidinecarboxylic acid,2-[(dimethylamino)carbonyl]-4-mercapto-,2-propen-1-yl ester, (2S,4S)- and methyl benzoate | 942-819-4 | - | 2019 | View substance registered dossier |
Lyondell Chemie Nederland B.V. | Deltseplein 27E 3013 AA Rotterdam Netherlands | Netherlands | Cease Manufacture | 1-tert-butoxypropan-2-ol | 406-180-0 | 57018-52-7 | 2020 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | No longer Valid | 1-tert-butoxypropan-2-ol | 406-180-0 | 57018-52-7 | 2022 | View substance registered dossier |
- | - | - | - | 1-tetradecanoylbenzotriazole | 437-790-5 | - | - | View substance registered dossier |
C.S.B. GmbH | Dujardinstr. 5 47829 Krefeld Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
ABCR GmbH | Im Schlehert 10 76187 Karlsruhe Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Chemservice S.A - (G5B1) | 13, Fausermillen 6689 Mertert Luxembourg | Luxembourg | Cease Manufacture | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2023 | View substance registered dossier |
Ferro GmbH | Gutleutstr.215 60327 Frankfurt am Main Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Henkel Global Supply Chain B.V. | Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands | Netherlands | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Du Pont de Nemours (Deutschland) GmbH | Hugenottenallee 175 D-63263 Neu-Isenburg Hesse Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
C.S.B. GmbH 0271 | Dujardinstr. 5 47829 Krefeld Nordrhein-Westfalen Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Du Pont (U.K.) Limited | London Road 4th Floor, Kings Court SG1 2NG Stevenage Hertfordshire United Kingdom | United Kingdom | No longer Valid | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2021 | View substance registered dossier |
Specialty Electronic Materials Netherlands BV | Baanhoekweg 22 3313 LA Dordrecht Netherlands | Netherlands | Cease Manufacture | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2021 | View substance registered dossier |
SIGMA-ALDRICH CHEMIE GMBH | Riedstrasse 2 89555 Steinheim Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
SNF SA | ZAC de Milieux 42163 Andrézieux France | France | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
DyStar Colours Distribution GmbH | Am Prime-Parc 12 65479 Raunheim Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Industex S.L. | Avenida Paises Catalanes nº 34, 8th floor 08950 Esplugas de Llobregat Barcelona Spain | Spain | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
KTR Europe GmbH | Mergenthalerallee 77 65760 HE Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland | Ireland | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
3M France SAS | 1 Parvis de l'Innovation CS 20203 95006 Cergy-Pontoise Cedex France | France | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Merck Life Science A/S | Vandtårnsvej 62A 2860 Søborg Denmark | Denmark | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Colgate Palmolive Services (Poland) Sp.Zo.o / Mexico | ul. Tasmowa 7 02-677 Warsaw Poland | Poland | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Wilkinson Sword GmbH | Schuetzenstr. 110 42659 Solingen NRW Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
KTR Europe GmbH | Mergenthalerallee 77 65760 Eschborn Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
BOSTIK S.A. NW | 420, rue d’Estienne d’Orves 92705 Colombes Cedex France | France | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Nor-Cote International Ltd | Unit 8, Warrior Park, Eagle Close, Chandlers Ford Industrial Estate, SO53 4NF Eastleigh Hampshire United Kingdom | United Kingdom | No longer Valid | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2021 | View substance registered dossier |
Nouryon Surface Chemistry AB | Box 47067 40258 Göteborg Sweden | Sweden | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2021 | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2012; 2013; 2015 | View substance registered dossier |
Zebra A/S | Strandgade 71-73 1401 Copenhagen Denmark | Denmark | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
3M Belgium BVBA/SPRL (OR1) | Hermeslaan 7 1831 Diegem Belgium | Belgium | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2019 | View substance registered dossier |
Daikin Chemical Europe GmbH | Am Wehrhahn 50 40211 Duesseldorf Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Evonik Operations GmbH - ME01 | Rellinghauser Straße 1-11 45128 Essen Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
3M Deutschland GmbH | Carl-Schurz-Strasse 1 41453 Neuss Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Bostik Nederland B.V._01 | Zeggeveld #10 RP4705 Roosendaal Netherlands | Netherlands | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Chemical Inspection & Regulation Service Limited | Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Stafford-Miller (Ireland) Limited | Clocherane Youghal Road _ Dungarvan Waterford Ireland | Ireland | Cease Manufacture | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2021 | View substance registered dossier |
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2022 | View substance registered dossier |
KCC Europe GmbH | Hansaring 61 50670 Köln Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
[Confidential] | - | - | - | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
REACH24H CONSULTING GROUP | Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland | Ireland | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Ashland Services BV (OR2) | Noordweg 9 3336 LH Zwijndrecht Netherlands | Netherlands | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | 2013; 2015 | View substance registered dossier |
TIGI Haircare GmbH | Postfach 700331 70573 Stuttgart Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
Chemreach GmbH | Akazienweg 30 48317 Drensteinfurt Germany | Germany | Active | 1-vinyl-2-pyrrolidone | 201-800-4 | 88-12-0 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | 2235-00-9 | 2013; 2014; 2016; 2019; 2021 | View substance registered dossier |
Sun Chemical A/S 7 | Københavnsvej 112 4600 Køge Denmark | Denmark | Active | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | 2235-00-9 | - | View substance registered dossier |
Sakata INX España S.A. (JP) | C/ Mercaders 24-26. Pol.Ind.Riera de Caldes E-08184 Palau Solità i Plegamans Barcelona Spain | Spain | Active | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | 2235-00-9 | - | View substance registered dossier |
HP Printing and Computing Solutions S.L. | calle de José Echegaray 18 28232 Las Rozas de Madrid (Madrid) Spain | Spain | Active | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | 2235-00-9 | 2018 | View substance registered dossier |
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Active | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | 2235-00-9 | - | View substance registered dossier |
3M Belgium BVBA/SPRL (OR1) | Hermeslaan 7 1831 Diegem Belgium | Belgium | Active | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | 2235-00-9 | - | View substance registered dossier |
Labcorp Development SA 032 | Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain | Spain | Active | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | 2235-00-9 | 2019 | View substance registered dossier |
Ashland Services BV (OR2) | Noordweg 9 3336 LH Zwijndrecht Netherlands | Netherlands | Active | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | 2235-00-9 | 2014 | View substance registered dossier |
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Active | 1-vinylimidazole | 214-012-0 | 1072-63-5 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | 1-vinylimidazole | 214-012-0 | 1072-63-5 | 2014; 2019; 2020 | View substance registered dossier |
SNF SA | ZAC de Milieux 42163 Andrézieux France | France | Active | 1-vinylimidazole | 214-012-0 | 1072-63-5 | - | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | 1-{4-[2-(benzyloxy)ethoxy]phenyl}-1,2-diphenylbutane-1,4-diol | 939-875-7 | - | - | View substance registered dossier |
OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Active | 1-{4-[2-(benzyloxy)ethoxy]phenyl}-1,2-diphenylbutane-1,4-diol | 939-875-7 | - | 2017 | View substance registered dossier |
ACS DOBFAR S.p.A | Viale Addetta 4/12 20067 Tribiano Milano Italy | Italy | Active | 1-{[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium chloride | 477-080-2 | - | - | View substance registered dossier |
Corden Pharma Latina S.p.A. | Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy | Italy | Active | 1-{[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium chloride | 477-080-2 | - | - | View substance registered dossier |
Sandoz GmbH | Biochemiestr. 10 6250 Kundl Austria | Austria | Cease Manufacture | 1-{[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium chloride | 477-080-2 | - | 2021 | View substance registered dossier |
ACS DOBFAR S.p.A | Viale Addetta 4/12 20067 Tribiano Milano Italy | Italy | Active | 1-{[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium iodide hydrate (1:1:1) | 606-216-7 | 190651-18-4 | 2011; 2019 | View substance registered dossier |
Fine Organics Limited | Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom | United Kingdom | No longer Valid | 1-{[(methylsulphanyl)carbonyl]oxy}ethyl 2-methylpropanoate | 700-047-3 | 860035-07-0 | 2021 | View substance registered dossier |
INDUSTRIAL QUIMICA LASEM, S.A.U. | Avda. de la Industria, 7 08297 Castellgali Spain | Spain | Active | 1-{[1-({1-[(2,2-dimethylpropanoyl)oxy]propan-2-yl}oxy)propan-2-yl]oxy}propan-2-yl 2,2-dimethylpropanoate | 950-485-6 | - | - | View substance registered dossier |
QUIMICA SINTETICA, S.A. | C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain | Spain | Active | 1-{[2-(2,4-Difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole monomethanesulfonate | 617-843-0 | 86386-77-8 | 2009; 2011 | View substance registered dossier |
Roche Diagnostics GmbH | Sandhoferstrasse 116 68305 Mannheim Germany | Germany | Cease Manufacture | 1-{benzyl[2-(2-methoxyphenoxy)ethyl]amino}-3-(9H-carbazol-4-yloxy)propan-2-ol | 432-890-5 | 72955-94-3 | 2019 | View substance registered dossier |
ARCHIMICA S.P.A. | Viale Milano 86 26900 Lodi Italy Italy | Italy | Active | 1-β-D-arabinofuranosylcytosine hydrochloride | 200-713-9 | 69-74-9 | - | View substance registered dossier |
H. Lundbeck A/S | Ottiliavej 7-9 2500 Copenhagen Denmark | Denmark | Active | 10,10-dimethylanthracen-9(10H)-one | 226-666-4 | 5447-86-9 | 2020 | View substance registered dossier |
FARMAK, a.s. | Na vlcinci 16/3 779 00 Olomouc Czech Republic | Czech Republic | Active | 10,10-dimethylanthracen-9(10H)-one | 226-666-4 | 5447-86-9 | - | View substance registered dossier |
Aceto France SAS | 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France | France | Active | 10,11-dihydro-5H-dibenz[b,f]azepine | 207-787-1 | 494-19-9 | - | View substance registered dossier |
SAFIC ALCAN | 13 Cours Valmy 92977 Paris La Défense France | France | Active | 10,11-dihydro-5H-dibenz[b,f]azepine | 207-787-1 | 494-19-9 | - | View substance registered dossier |
Chemosyntha BV | Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium | Belgium | Active | 10,11-dihydro-5H-dibenz[b,f]azepine | 207-787-1 | 494-19-9 | - | View substance registered dossier |
SONEAS Chemicals Ltd. | Banyaleg Str. 47-59. H-1225 Budapest Hungary | Hungary | Active | 10,11-dihydro-5H-dibenz[b,f]azepine | 207-787-1 | 494-19-9 | - | View substance registered dossier |
sanofi chimie | 82 avenue Raspail 94250 Gentilly France | France | Active | 10,11-dihydro-5H-dibenz[b,f]azepine | 207-787-1 | 494-19-9 | - | View substance registered dossier |
Kemikos s.r.l. | Via Carolina Romani, 2/A 20091 Bresso (MI) Italy | Italy | Active | 10,11-dihydro-5H-dibenz[b,f]azepine | 207-787-1 | 494-19-9 | - | View substance registered dossier |
Corden Pharma Bergamo S.p.A. | Via Bergamo, 121 IT-24047 Treviglio BG Italy | Italy | Active | 10,11-dihydro-5H-dibenz[b,f]azepine | 207-787-1 | 494-19-9 | - | View substance registered dossier |
Novartis Integrated Services Limited | Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland | Ireland | Active | 10,11-dihydro-5H-dibenz[b,f]azepine | 207-787-1 | 494-19-9 | - | View substance registered dossier |
Clariant Production (France) S.A.S. | 21-23 rue du Petit Albi Bâtiment Le Cérès, Hall 303, CS 18545 95892 CergyCergy Pontoise Cedex France | France | Cease Manufacture | 10,12-dihydrobenz(de)imidazo(4',5':5,6)benzimidazo(1,2-a)isoquinoline-8,11-dione | 408-170-1 | 56279-27-7 | 2021 | View substance registered dossier |
Synthesia, a.s. | Semtín103 53002 Pardubice Czech Republic | Czech Republic | Active | 10,12-dihydrobenz(de)imidazo(4',5':5,6)benzimidazo(1,2-a)isoquinoline-8,11-dione | 408-170-1 | 56279-27-7 | - | View substance registered dossier |
ICL-IP Terneuzen B.V. (M) | Frankrijkweg 6, Havens/Docks 1205-45308 BJ 4538 BJ Terneuzen Netherlands | Netherlands | Active | 10-(2,5-Dihydroxyphenyl)-10H-9-oxa-10-phospha-phenantbrene-10-oxide | 619-409-6 | 99208-50-1 | 2019; 2022 | View substance registered dossier |
Trifarma S.p.A. | Via G. Guarini Matteucci 1 20162 Milan (MI) Italy | Italy | Active | 10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine | 201-578-9 | 84-97-9 | - | View substance registered dossier |
EGIS Pharmaceuticals PLC | Keresztúri út 30-38 H-1106 Budapest Hungary | Hungary | Active | 10-[4-(2-chloroethyl)piperazin-1-yl]-2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,9,12,14-heptaene | 609-095-9 | 352232-17-8 | - | View substance registered dossier |
Industriale Chimica s.r.l. | via E.H. Grieg, 13 21074 Saronno (VA) Italy | Italy | Active | 10-hydroxy-1-(2-hydroxy-3,4-dimethoxy-6-methylphenyl) decan-1-one | 700-045-2 | 104966-97-4 | - | View substance registered dossier |
Johnson & Johnson Vision Care Ireland Unlimited Company (UC) | National Technology Park Plassey none Limerick Co Limerick Ireland | Ireland | Active | 10-hydroxy-2,2,4-trimethyl-4-[(trimethylsilyl)oxy]-3,8-dioxa-2,4-disilaundecan-11-yl 2-methylprop-2-enoate; 11-hydroxy-2,2,4-trimethyl-4-[(trimethylsilyl)oxy]-3,8-dioxa-2,4-disilaundecan-10-yl 2-methylprop-2-enoate | 700-334-3 | - | 2009; 2013; 2015; 2018 | View substance registered dossier |
Yordas GmbH | Äußere Nürnberger Straße 62 91301 Forchheim Germany | Germany | Active | 10-hydroxy-2,2,4-trimethyl-4-[(trimethylsilyl)oxy]-3,8-dioxa-2,4-disilaundecan-11-yl 2-methylprop-2-enoate; 11-hydroxy-2,2,4-trimethyl-4-[(trimethylsilyl)oxy]-3,8-dioxa-2,4-disilaundecan-10-yl 2-methylprop-2-enoate | 700-334-3 | - | - | View substance registered dossier |
ERM_GmbH_OR14_GUK | Siemenstrasse 9. 63263 Neu Isenburg Hessen Germany | Germany | Active | 10-hydroxy-2,2,4-trimethyl-4-[(trimethylsilyl)oxy]-3,8-dioxa-2,4-disilaundecan-11-yl 2-methylprop-2-enoate; 11-hydroxy-2,2,4-trimethyl-4-[(trimethylsilyl)oxy]-3,8-dioxa-2,4-disilaundecan-10-yl 2-methylprop-2-enoate | 700-334-3 | - | - | View substance registered dossier |
[Confidential] | - | - | - | 10-hydroxy-2,2,4-trimethyl-4-[(trimethylsilyl)oxy]-3,8-dioxa-2,4-disilaundecan-11-yl 2-methylprop-2-enoate; 11-hydroxy-2,2,4-trimethyl-4-[(trimethylsilyl)oxy]-3,8-dioxa-2,4-disilaundecan-10-yl 2-methylprop-2-enoate | 700-334-3 | - | - | View substance registered dossier |
Teva Czech Industries s.r.o. | Ostravska 29/305 74770 Opava - Komarov Czech Republic | Czech Republic | Active | 10-methoxy-1,6-dimethylergoline-8β-methanol | 252-405-9 | 35155-28-3 | - | View substance registered dossier |
OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Cease Manufacture | 10-methoxy-1,6-dimethylergoline-8β-methanol | 252-405-9 | 35155-28-3 | 2022 | View substance registered dossier |
Novartis Integrated Services Limited | Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland | Ireland | Active | 10-methoxy-5H-dibenz[b,f]azepine | 225-172-6 | 4698-11-7 | - | View substance registered dossier |
Novartis Ringaskiddy Limited | . . Ringaskiddy County Cork Ireland | Ireland | Cease Manufacture | 10-methoxy-5H-dibenz[b,f]azepine | 225-172-6 | 4698-11-7 | 2015 | View substance registered dossier |
Novartis Grimsby Limited | Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom | United Kingdom | No longer Valid | 10-methoxy-5H-dibenz[b,f]azepine | 225-172-6 | 4698-11-7 | 2021 | View substance registered dossier |
Trifarma S.p.A. | Via G. Guarini Matteucci 1 20162 Milan (MI) Italy | Italy | Active | 10-methoxy-5H-dibenz[b,f]azepine | 225-172-6 | 4698-11-7 | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 10-methoxy-5H-dibenz[b,f]azepine | 225-172-6 | 4698-11-7 | 2019 | View substance registered dossier |
OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Active | 10-methoxy-6-methylergoline-8β-methanol | 252-385-1 | 35121-60-9 | - | View substance registered dossier |
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Active | 10-oxo-10H-dibenzo[b,e]thiopyran-4-carboxylic acid | 849-175-2 | 51762-56-2 | - | View substance registered dossier |
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED | Regus Harcourt Centre D02 HW77 Dublin Ireland | Ireland | Active | 10-oxo-10H-dibenzo[b,e]thiopyran-4-carboxylic acid | 849-175-2 | 51762-56-2 | 2020 | View substance registered dossier |
Evonik Operations GmbH | Rellinghauser Straße 1-11 45128 Essen Germany | Germany | Active | 10-Undecenamide, N-[3-(dimethylamino)propyl]- | 613-971-6 | 66654-01-1 | - | View substance registered dossier |
Hallstar Italia Srl con socio unico | Piazza Meda, 3 20121 Milano Lombardia Italy | Italy | Active | 10-undecenyl 2-cyano-3,3-diphenylpropenoate | 700-604-0 | 947701-81-7 | - | View substance registered dossier |
Biesterfeld Spezialchemie GmbH | Ferdinandstr. 41 20095 Hamburg Germany | Germany | Active | 10H-pyrido[3,2-b](1,4)benzothiazine | 205-973-7 | 261-96-1 | - | View substance registered dossier |
Minakem Dunkerque Production | 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France | France | Cease Manufacture | 11,11-dimethyl-5-oxa-3-thia-4-azatetracyclo[6.2.1.01,6.04,6]undecane-3,3-dione | 800-131-0 | 104372-31-8 | 2019 | View substance registered dossier |
In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).
ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.
As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
In the portal results table are presented:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- Link to the full factsheet.
A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.
RELATED INFORMATION
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Welcome to the REACH Registered Substance Factsheets
Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.
Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.
Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.
Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
All substances table
The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.
The following columns are presented in the “All substances” table:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- ‘Eye’ icon linking to the full factsheet.
Searching
The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.
Substance identity
In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.
Administrative data
In this block you can search by administrative information relating to REACH registered substance factsheets:
- Registration type – picklist of Full, Intermediate, NONS
- Registration status – picklist of Active, Cease Manufacture, No longer valid
- Submission type – Individual or Joint
- Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
- First published date – the date when a REACH registration factsheet was first published
- Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
- Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
- Registrant / supplier name – where available and not claimed confidential
- Registration number – where available and not claimed confidential
- Registrant address – where available and not claimed confidential
Substance data
In this block you can search by substance related data from REACH registered substance factsheets:
- Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
- Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
- Substance has nanoform – picklist of Yes, No
- PBT assessment outcome – picklist of all possible PBT assessment outcomes
- CSA performed – picklist of Yes, No
Use and exposure
In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.
Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.
Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.
Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.
With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.
The factsheets
There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.
The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.
The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.
In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.
Next is a page covering administrative type information from the data submitted, including:
Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.
Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.
Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.
Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.
The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.