1-O-β-(2 ,3-di-O-alka(e)noyl-6 -O-acetyl-D-mannopyranosyl)-D-erythritol

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

19 December 2018 to 21 February 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of Inspection: 21 August 2018 Date of Issue: 19 November 2018

Type of method:

air comparison pycnometer (for solids)

Key result

Type:

relative density

Density:

1.09 other: dimensionless

Temp.:

19 °C

Type:

density

Density:

1 090 kg/m³

Temp.:

19 °C

Calibration

The pressure readings and the calculated volume for the reference and sample cells are shown in the following table:

Table 1

Determination	P1(psig)	P2(psig)	P3(psig)	P4(psig)	Reference Cell Volume (cm^3)	Sample Cell Volume (cm^3)
1	17.060	6.455	16.290	8.068	90.665	148.954
2	17.089	6.470	17.058	8.450	90.848	149.105
3	17.102	6.478	17.092	8.468	90.991	149.226

Mean reference cell volume: 90.834 cm³

Mean sample cell volume: 149.095 cm³

As the reference cell volume and sample cell volume were within defined tolerances (90.953 ± 1.0 cm³and 149.225 ± 1.0 cm³for the reference and sample cell volumes respectively) the gas comparison pycnometer was considered acceptable for use.

Sample

The mass of the vessel, vessel and test item, and the calculated mass of test item are shown in the following table:

Table 2

Determination	Mass of Vessel (g)	Mass of Vessel and Test Item (g)	Mass of Test Item (g)
1	31.2896	59.8184	28.5288
2	33.4166	58.9079	25.4913

The pressure readings obtained for the vessel and vessel containing test item are shown in the following table:

Table 3

Det^n	Rep	Vessel			Vessel and Test Item
		P1(sample) (psig)	P2(sample) (psig)	Volume (cm^3)	P3(sample) (psig)	P4(sample) (psig)	Volume (cm^3)
1	A	17.130	6.901	14.257	16.967	7.730	40.552
	B	17.161	6.909	14.111	16.989	7.737	40.474
	C	17.258	6.948	14.109	17.062	7.768	40.417
2	A	16.930	6.851	15.264	17.003	7.671	38.592
	B	17.174	6.945	15.111	17.030	7.681	38.535
	C	17.033	6.885	15.014	17.026	7.679	38.530

The calculated volumes and density obtained are shown in the following table:

Table 4

Determination	Mass of Vessel (g)	Mass of Vessel and Test Item (g)	Mass of Test Item (g)	Density (kg/m^3)
1	14.159	40.481	26.322	1.08 x 10^3
2	15.130	38.552	23.423	1.09 x 10^3

Mean density: 1.09 x 10³ kg/m³

Relative density: 1.09

Temperature: 19.0 ± 0.5°C

Conclusions:

The density of the test item has been determined to be 1090 kg/m3 at 19.0 ± 0.5°C and a relative density of 1.09.

Executive summary:

The density of the test item has been determined to be 1.09 x 10³kg/m³at 19.0 ± 0.5 °C, relative density of 1.09, using a gas comparison pycnometer, designed to be compatible with Method A.3 Relative Density of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 109 of the OECD Guidelines for Testing of Chemicals, 02 October 2012.

Description of key information

Relative density: 1.09 at 19°C; OECD 109; Fox, J. M. (2019)