Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 500-300-6 | CAS number: 111411-00-8
Guidance on Safe Use
Guidance on Safe Use
Administrative data
First-aid measures
- General advice:
First Aid responders should pay attention to self-protection and use the recommended protective clothing (chemical resistant gloves, splash protection). If potential for exposure exists refer to Section 8 for specific personal protective equipment.
- Following inhalation:
Move person to fresh air; if effects occur, consult a physician.
- Following skin contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing. Seek medical attention if symptoms occur or irritation persists. Wash clothing before reuse. Discard items which cannot be decontaminated, including leather articles such as shoes, belts and watchbands. Suitable emergency safety shower facility should be immediately available.
- Following eye contact:
Wash immediately and continuously with flowing water for at least 30 minutes. Remove contact lenses after the first 5 minutes and continue washing. Obtain prompt medical consultation, preferably from an ophthalmologist. Suitable emergency eye wash facility should be immediately available.
- Following ingestion:
Do not induce vomiting. Give one cup (8 ounces or 240 ml) of water or milk if available and transport to a medical facility. Do not give anything by mouth unless the person is fully conscious.
- Most important symptoms and effects:
Aside from the information found under Description of first aid measures (above) and Indication of immediate medical attention and special treatment needed (below), any additional important symptoms and effects are described in Toxicology Information.
First Aid responders should pay attention to self-protection and use the recommended protective clothing (chemical resistant gloves, splash protection). If potential for exposure exists refer to Section 8 for specific personal protective equipment.
- Following inhalation:
Move person to fresh air; if effects occur, consult a physician.
- Following skin contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing. Seek medical attention if symptoms occur or irritation persists. Wash clothing before reuse. Discard items which cannot be decontaminated, including leather articles such as shoes, belts and watchbands. Suitable emergency safety shower facility should be immediately available.
- Following eye contact:
Wash immediately and continuously with flowing water for at least 30 minutes. Remove contact lenses after the first 5 minutes and continue washing. Obtain prompt medical consultation, preferably from an ophthalmologist. Suitable emergency eye wash facility should be immediately available.
- Following ingestion:
Do not induce vomiting. Give one cup (8 ounces or 240 ml) of water or milk if available and transport to a medical facility. Do not give anything by mouth unless the person is fully conscious.
- Most important symptoms and effects:
Aside from the information found under Description of first aid measures (above) and Indication of immediate medical attention and special treatment needed (below), any additional important symptoms and effects are described in Toxicology Information.
Fire-fighting measures
- Suitable extinguishing media:
Water fog or fine spray. Dry chemical fire extinguishers. Carbon dioxide fire extinguishers. Foam. Alcohol resistant foams (ATC type) are preferred. General purpose synthetic foams (including AFFF) or protein foams may function, but will be less effective.
- Unsuitable extinguishing media:
Do not use direct water stream. May spread fire.
- Special hazards arising from the substance or mixture:
Hazardous combustion products: During a fire, smoke may contain the original material in addition to combustion products of varying composition which may be toxic and/or irritating. Combustion products may include and are not limited to: Nitrogen oxides. Carbon monoxide. Carbon dioxide.
Unusual Fire and Explosion Hazards: Container may rupture from gas generation in a fire situation. Violent steam generation or eruption may occur upon application of direct water stream to hot liquids.
- Advice for fire fighter:
Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. Use water spray to cool fire exposed containers and fire affected zone until fire is out and danger of reignition has passed. Fight fire from protected location or safe distance. Consider the use of unmanned hose holders or monitor nozzles. Immediately withdraw all personnel from the area in case of rising sound from venting safety device or discoloration of the container. Burning liquids may be extinguished by dilution with water. Do not use direct water stream. May spread fire. Move container from fire area if this is possible without hazard. Burning liquids may be moved by flushing with water to protect personnel and minimize property damage. Contain fire water run-off if possible. Fire water run-off, if not contained, may cause environmental damage.
Special protective equipment for firefighters: Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, boots, and gloves). Avoid contact with this material during fire fighting operations. If contact is likely, change to full chemical resistant fire fighting clothing with self-contained breathing apparatus. If this is not available, wear full chemical resistant clothing with self-contained breathing apparatus and fight fire from a remote location. For protective equipment in post-fire or non-fire clean-up situations, refer to the relevant sections.
Water fog or fine spray. Dry chemical fire extinguishers. Carbon dioxide fire extinguishers. Foam. Alcohol resistant foams (ATC type) are preferred. General purpose synthetic foams (including AFFF) or protein foams may function, but will be less effective.
- Unsuitable extinguishing media:
Do not use direct water stream. May spread fire.
- Special hazards arising from the substance or mixture:
Hazardous combustion products: During a fire, smoke may contain the original material in addition to combustion products of varying composition which may be toxic and/or irritating. Combustion products may include and are not limited to: Nitrogen oxides. Carbon monoxide. Carbon dioxide.
Unusual Fire and Explosion Hazards: Container may rupture from gas generation in a fire situation. Violent steam generation or eruption may occur upon application of direct water stream to hot liquids.
- Advice for fire fighter:
Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. Use water spray to cool fire exposed containers and fire affected zone until fire is out and danger of reignition has passed. Fight fire from protected location or safe distance. Consider the use of unmanned hose holders or monitor nozzles. Immediately withdraw all personnel from the area in case of rising sound from venting safety device or discoloration of the container. Burning liquids may be extinguished by dilution with water. Do not use direct water stream. May spread fire. Move container from fire area if this is possible without hazard. Burning liquids may be moved by flushing with water to protect personnel and minimize property damage. Contain fire water run-off if possible. Fire water run-off, if not contained, may cause environmental damage.
Special protective equipment for firefighters: Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, boots, and gloves). Avoid contact with this material during fire fighting operations. If contact is likely, change to full chemical resistant fire fighting clothing with self-contained breathing apparatus. If this is not available, wear full chemical resistant clothing with self-contained breathing apparatus and fight fire from a remote location. For protective equipment in post-fire or non-fire clean-up situations, refer to the relevant sections.
Accidental release measures
- Personal precautions:
Evacuate area. Only trained and properly protected personnel must be involved in clean-up operations. Keep upwind of spill. Ventilate area of leak or spill.
- Protective equipment and emergency procedures:
Use appropriate safety equipment.
- Environmental precautions:
Prevent from entering into soil, ditches, sewers, waterways and/or groundwater.
- Methods and material for containment and cleaning up:
Contain spilled material if possible. Absorb with materials such as: Sand. Collect in suitable and properly labeled containers.
Evacuate area. Only trained and properly protected personnel must be involved in clean-up operations. Keep upwind of spill. Ventilate area of leak or spill.
- Protective equipment and emergency procedures:
Use appropriate safety equipment.
- Environmental precautions:
Prevent from entering into soil, ditches, sewers, waterways and/or groundwater.
- Methods and material for containment and cleaning up:
Contain spilled material if possible. Absorb with materials such as: Sand. Collect in suitable and properly labeled containers.
Handling and storage
- Precautions for safe handling:
Do not get in eyes, on skin, on clothing. Avoid breathing vapor. Do not swallow. Avoid prolonged contact with eyes, skin and clothing. Keep container closed. Use with adequate ventilation. Wash thoroughly after handling. Spills of these organic materials on hot fibrous insulations may lead to lowering of the autoignition temperatures possibly resulting in spontaneous combustion.
- Conditions for safe storage, including any incompatibilities:
Store in a cool, dry place.
Do not get in eyes, on skin, on clothing. Avoid breathing vapor. Do not swallow. Avoid prolonged contact with eyes, skin and clothing. Keep container closed. Use with adequate ventilation. Wash thoroughly after handling. Spills of these organic materials on hot fibrous insulations may lead to lowering of the autoignition temperatures possibly resulting in spontaneous combustion.
- Conditions for safe storage, including any incompatibilities:
Store in a cool, dry place.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2289
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Marine transport (UN RTDG/IMDG)
- UN number:
- 2289
Shipping information
- Proper shipping name and description:
- ISOPHORONEDIAMINE MIXTURE(P-tert-butylphenol)
- Chemical name:
- P-tert-butylphenol
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2289
Shipping information
- Proper shipping name and description:
- Isophoronediamine mixture(P-tert-butylphenol)
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Exposure controls / personal protection
1. Technical protection measures
Engineering controls: Use local exhaust ventilation, or other engineering controls to maintain airborne levels below exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, general ventilation should be sufficient for most operations. Local exhaust ventilation may be necessary for some operations.
2. Organisational protection measures
3. Hand, feet and body protection
Use chemical resistant gloves classified under Standard EN374: Protective gloves against chemicals and micro-organisms. Examples of preferred glove barrier materials include: Chlorinated polyethylene. Polyethylene. Ethyl vinyl alcohol laminate ("EVAL"). Styrene/butadiene rubber. Examples of acceptable glove barrier materials include: Butyl rubber. Natural rubber ("latex"). Neoprene. Nitrile/butadiene rubber ("nitrile" or "NBR"). Polyvinyl chloride ("PVC" or "vinyl"). Viton. Avoid gloves made of: Polyvinyl alcohol ("PVA"). When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time greater than 240 minutes according to EN 374) is recommended. When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374) is recommended. Glove thickness alone is not a good indicator of the level of protection a glove provides against a chemical substance as this level of protection is also highly dependent on the specific composition of the material that the glove is fabricated from. The thickness of the glove must, depending on model and type of material, generally be more than 0.35 mm to offer sufficient protection for prolonged and frequent contact with the substance. As an exception to this general rule it is known that multilayer laminate gloves may offer prolonged protection at thicknesses less than 0.35 mm. Other glove materials with a thickness of less than 0.35 mm may offer sufficient protection when only brief contact is expected. NOTICE: The selection of a specific glove for a particular application and duration of use in a workplace should also take into account all relevant workplace factors such as, but not limited to: Other chemicals which may be handled, physical requirements (cut/puncture protection, dexterity, thermal protection), potential body reactions to glove materials, as well as the instructions/specifications provided by the glove supplier.
6. Eye, face protection
Use chemical goggles. Chemical goggles should be consistent with EN 166 or equivalent. If exposure causes eye discomfort, use a full-face respirator.
7. Respiratory protection
Respiratory protection should be worn when there is a potential to exceed the exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, wear respiratory protection when adverse effects, such as respiratory irritation or discomfort have been experienced, or where indicated by your risk assessment process. For most conditions, no respiratory protection should be needed; however, if handling at elevated temperatures without sufficient ventilation, use an approved air-purifying respirator.
Use the following CE approved air-purifying respirator: Organic vapor cartridge with a particulate pre-filter, type AP2.
Engineering controls: Use local exhaust ventilation, or other engineering controls to maintain airborne levels below exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, general ventilation should be sufficient for most operations. Local exhaust ventilation may be necessary for some operations.
2. Organisational protection measures
3. Hand, feet and body protection
Use chemical resistant gloves classified under Standard EN374: Protective gloves against chemicals and micro-organisms. Examples of preferred glove barrier materials include: Chlorinated polyethylene. Polyethylene. Ethyl vinyl alcohol laminate ("EVAL"). Styrene/butadiene rubber. Examples of acceptable glove barrier materials include: Butyl rubber. Natural rubber ("latex"). Neoprene. Nitrile/butadiene rubber ("nitrile" or "NBR"). Polyvinyl chloride ("PVC" or "vinyl"). Viton. Avoid gloves made of: Polyvinyl alcohol ("PVA"). When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time greater than 240 minutes according to EN 374) is recommended. When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374) is recommended. Glove thickness alone is not a good indicator of the level of protection a glove provides against a chemical substance as this level of protection is also highly dependent on the specific composition of the material that the glove is fabricated from. The thickness of the glove must, depending on model and type of material, generally be more than 0.35 mm to offer sufficient protection for prolonged and frequent contact with the substance. As an exception to this general rule it is known that multilayer laminate gloves may offer prolonged protection at thicknesses less than 0.35 mm. Other glove materials with a thickness of less than 0.35 mm may offer sufficient protection when only brief contact is expected. NOTICE: The selection of a specific glove for a particular application and duration of use in a workplace should also take into account all relevant workplace factors such as, but not limited to: Other chemicals which may be handled, physical requirements (cut/puncture protection, dexterity, thermal protection), potential body reactions to glove materials, as well as the instructions/specifications provided by the glove supplier.
6. Eye, face protection
Use chemical goggles. Chemical goggles should be consistent with EN 166 or equivalent. If exposure causes eye discomfort, use a full-face respirator.
7. Respiratory protection
Respiratory protection should be worn when there is a potential to exceed the exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, wear respiratory protection when adverse effects, such as respiratory irritation or discomfort have been experienced, or where indicated by your risk assessment process. For most conditions, no respiratory protection should be needed; however, if handling at elevated temperatures without sufficient ventilation, use an approved air-purifying respirator.
Use the following CE approved air-purifying respirator: Organic vapor cartridge with a particulate pre-filter, type AP2.
Stability and reactivity
1. Reactivity
No data available
2. Chemical stability
Stable under recommended storage conditions (5-30°C; 12 months; cool,dry place)
3. Possibility of hazardous reactions
Polymerization will not occur.
4. Conditions to avoid
Exposure to elevated temperatures can cause product to decompose. Generation of gas during decomposition can cause pressure in closed systems. Reaction with carbon dioxide may form an amine carbamate. Smoke may be generated depending on vapor pressure of mixture. Product absorbs carbon dioxide from the air.
5. Incompatible materials
Avoid contact with oxidizing materials. Avoid contact with: Acids. Acrylates. Alcohols. Aldehydes. Halogenated hydrocarbons. Ketones. Nitrites. Avoid contact with metals such as: Brass. Bronze. Copper. Copper alloys.
6. Hazardous decomposition products
Decomposition products depend upon temperature, air supply and the presence of other materials. Decomposition products can include and are not limited to: Aromatic compounds. Ammonia. Ethylenediamine. Volatile amines. Hydrocarbons. Phenolics.
No data available
2. Chemical stability
Stable under recommended storage conditions (5-30°C; 12 months; cool,dry place)
3. Possibility of hazardous reactions
Polymerization will not occur.
4. Conditions to avoid
Exposure to elevated temperatures can cause product to decompose. Generation of gas during decomposition can cause pressure in closed systems. Reaction with carbon dioxide may form an amine carbamate. Smoke may be generated depending on vapor pressure of mixture. Product absorbs carbon dioxide from the air.
5. Incompatible materials
Avoid contact with oxidizing materials. Avoid contact with: Acids. Acrylates. Alcohols. Aldehydes. Halogenated hydrocarbons. Ketones. Nitrites. Avoid contact with metals such as: Brass. Bronze. Copper. Copper alloys.
6. Hazardous decomposition products
Decomposition products depend upon temperature, air supply and the presence of other materials. Decomposition products can include and are not limited to: Aromatic compounds. Ammonia. Ethylenediamine. Volatile amines. Hydrocarbons. Phenolics.
Disposal considerations
This product, when being disposed of in its unused and uncontaminated state should be treated as a hazardous waste according to EC Directive 2008/98/EC. Any disposal practices must be in compliance with all national and provincial laws and any municipal or local by-laws governing hazardous waste. For used, contaminated and residual materials additional evaluations may be required. Do not dump into any sewers, on the ground, or into any body of water.
The definitive assignment of this material to the appropriate EWC group and thus its proper EWC code will depend on the use that is made of this material. Contact the authorized waste disposal services.
The definitive assignment of this material to the appropriate EWC group and thus its proper EWC code will depend on the use that is made of this material. Contact the authorized waste disposal services.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
