Registration Dossier
Registration Dossier
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EC number: 280-445-7 | CAS number: 83411-71-6
Endpoint summary
Administrative data
Description of key information
Non-readily biodegradable
Hydrolytically stable
Log Koc =1.42 (pH 7); Koc = 26.3 l/kg
BCF < 7 l/kg (whole body w.w.); < 63 l/kg (whole body w.w.) (steady state)
Additional information
The substance is considered as non-readily biodegradable, as only 5.9 % biodegradation was observed during the 28 day study conducted according to the OECD Guideline 301D.
The substance is also considered as hydrolytically stable at pH 4, 7 and 9 and the estimated half-life at 25 °C of the test item for pH 4, 7 and 9 has been shown to be greater than 1 year. Less than 10 % hydrolysis was observed after 5 days at 50 °C in the study conducted according to the OECD 121.
The adsorption coefficient (LogKoc) of the substance was calculated by QSAR as 3.64 at pH 1.8 and as 1.42 at pH 7.
Its biodegradation in water and sediment based on simulation tests and its biodegradation in soil was not evaluated considering that a direct and an indirect exposure to sediment and soil is not expected.
The bioaccumulation of the substance was evaluated according to a standard guideline with GLP. The bioconcentration factors (BCF) were < 7 and < 63 for the first (0.2 mg/l) and the second (0.02 mg/l) concentration areas. No bioaccumulation in fish and aquatic species is therefore expected.
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