Registration Dossier
Registration Dossier
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EC number: 230-525-2 | CAS number: 7173-51-5
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- fish life cycle toxicity
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Reason / purpose for cross-reference:
- data waiving: supporting information
- Reason / purpose for cross-reference:
- data waiving: supporting information
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
Description of key information
Key value for chemical safety assessment
Marine water fish
Marine water fish
- Effect concentration:
- 0.032 mg/L
Additional information
Long term toxicity to fish is considered necessary for the following reasons: The test substance is readily biodegradable and has a low bioaccumulation potential, with a measured log Pow of 2.59 (estimated BCF is 71). The available studies show that fish are ca. 10 times less sensitive than algae and Daphnia in acute toxicity testing. Data presented in the DDAC assessment report for Product Type 8 conducted under Directive 98/8/EC (evaluating Competent Authority: Italy, June 2015, attached in Section 13 of the IUCLID dataset) indicate a NOEC from an early life stage study with Danio rerio of 0.0322 mg a.i./L. The NOEC/EC10 from long-term toxicity testing in Daphnia and algae are lower, i.e. 0.021 and 0.020 mg a.i./L, respectively, so that algae rather than fish data is used for PNEC derivation.
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