Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-521-7 | CAS number: 617-62-9
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
The 14-day LC50 on earthworms (Eisenia foetida) was higher than 1000 mg/kg d.w.; implying that 2-methylglutaric acid is not harmful to earthworms.
Key value for chemical safety assessment
Additional information
An experimental study, scored as Klimisch 1, was selected as a key study. It was performed in compliance with GLP according to OECD 207 test guideline. Under REACH, such study is not required because 2-methylglutaric acid (i) is not intentionally applied to soil, (ii) has a low volatility potential from water and because (iii) there is no indication for high adsorption (Log Kow < 5, Log Koc < 4), high persistence (rapidly degradable) or acute toxicity to aquatic organisms (L/EC50 > 100 mg/L in the three trophic levels). The study was nevertheless provided here because it was performed for the purpose of another regulation, a Chinese notification, which required the performance of this test in a Chinese laboratory.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
