Registration Dossier
Registration Dossier
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EC number: 201-074-9 | CAS number: 77-99-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72-h EbC50 of trimethylolpropane to Pseudokirchneriella subcapitata was
determined to be greater than 1000 mg/L (based on nominal concentrations).
Key value for chemical safety assessment
Additional information
Key study
The toxicity of trimethylopropane on the green algae Pseudokirchneriella subcapitata (reported as Selenastrum carpicornutum) was tested according to an OECD guideline. The 72-h EbC50 was determined to be greater than 1000 mg/L (based on nominal concentrations). Being performed by EA Japan according to a OECD-Guideline, the study is considered to be acceptable.
Reference: EA Japan/SIDS, <= 1994
Supporting study
The toxicity of trimethylolpropane to Pseudokirchnerella subcapitata
was determined within a test duration of 14 d. Cells were counted on day 3, 6, 10 and 12. A NOEC of 1,000 mg/L may be derived from the graph provided in the publication. The authors reported EC >1000 mg/L, which are interpreted in that way, that all effects were above 1000 mg/L.
As only a short abstract is available, the reliablity cannot be assessed.
Reference: Walton & Davis, 1980
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