EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 26 April 2024. Database contains 4691 unique substances/entries.

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Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC
Mycoplasma hominis	-	-		B Bacteria and similar species
Mycoplasma caviae	-	-		B Bacteria and similar species
Mycobacterium xenopi	-	-		B Bacteria and similar species
Mycobacterium ulcerans	-	-		B Bacteria and similar species
Mycobacterium tuberculosis	-	-		B Bacteria and similar species
Mycobacterium szulgai	-	-		B Bacteria and similar species
Mycobacterium simiae	-	-		B Bacteria and similar species
Mycobacterium scrofulaceum	-	-		B Bacteria and similar species
Mycobacterium paratuberculosis	-	-		B Bacteria and similar species
Mycobacterium microti	-	-		B Bacteria and similar species
Mycobacterium marinum	-	-		B Bacteria and similar species
Mycobacterium malmoense	-	-		B Bacteria and similar species
Mycobacterium leprae	-	-		B Bacteria and similar species
Mycobacterium kansasii	-	-		B Bacteria and similar species
Mycobacterium fortuitum	-	-		B Bacteria and similar species
Mycobacterium chelonae	-	-		B Bacteria and similar species
Mycobacterium bovis (except BCG strain)	-	-		B Bacteria and similar species
Mycobacterium avium/intracellulare	-	-		B Bacteria and similar species
Mycobacterium africanum	-	-		B Bacteria and similar species
myclobutanil(ISO);2-(4-chlorophenyl)-2-(1H-1,2,4- triazol-1-ylmethyl)hexanenitrile SYSTHANE TECHNICAL	410-400-0	88671-89-0	Repr. 2; Acute Tox. 4; Eye Irrit. 2
musk xylene; 5-tert-butyl-2,4,6-trinitro-m-xylene	201-329-4	81-15-2	Expl. 1.1; Carc. 2
musk ketone; 3,5-dinitro-2,6-dimethyl-4-tert-butylacetophenone; 4'-tert-butyl-2', 6'-dimethyl-3',; 5'-dinitroacetophenone	201-328-9	81-14-1	Carc. 2
muscalure; cis-tricos-9-ene	248-505-7	27519-02-4	Skin Sens. 1B
Mumps virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Mucambo virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
morphothion (ISO); O, O-dimethyl-S-(morpholinocarbonylmethyl) phosphorodithioate	205-628-0	144-41-2	Acute Tox. 3
morpholine-4-carbonyl chloride	239-213-0	15159-40-7	Carc. 2; Eye Irrit. 2; Skin Irrit. 2
morpholine	203-815-1	110-91-8	Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
Morganella morganii	-	-		B Bacteria and similar species
morfamquat sulfate	-	29873-36-7	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
morfamquat dichloride	225-062-8	4636-83-3	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
morfamquat (ISO); 1,1'-bis(3,5-dimethylmorpholinocarbonylmethyl)-4,4'-bipyridilium ion	-	7411-47-4	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
Mopeia virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
monuron (ISO); 3-(4-chlorophenyl)-1,1-dimethylurea	205-766-1	150-68-5	Carc. 2; Acute Tox. 4
monosodium 3-cyano-5-fluoro-6-hydroxypyridine-2-olate	429-570-2	213990-58-0	Skin Sens. 1
monolinuron (ISO); 3-(4-chlorophenyl)-1-methoxy-1-methylurea	217-129-5	1746-81-2	Acute Tox. 4; STOT RE 2
monocrotophos (ISO); dimethyl-1-methyl-2-(methylcarbamoyl)vinyl phosphate	230-042-7	6923-22-4	Muta. 2; Acute Tox. 2; Acute Tox. 3
monobenzone; 4-hydroxyphenyl benzyl ether; hydroquinone monobenzyl ether	203-083-3	103-16-2	Eye Irrit. 2; Skin Sens. 1
monoalkyl or monoaryl or monoalkylaryl esters of acrylic acid with the exception of those specified elsewhere in this Annex	-	-	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
monoalkyl or monoaryl or monoalkyaryl esters of methacrylic acid with the exception of those specified elsewhere in this Annex	-	-	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
mono[2-(dimethylamino)ethyl]monohydrogen-2-(hexadec-2-enyl)butanedioate and/or mono[2-(dimethylamino)ethyl]monohydrogen-3-(hexadec-2-enyl)butanedioate Z-22	415-880-5	779343-34-9	Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
mono-methylamine;mono-methylamine ... %	200-820-0	74-89-5	Flam. Gas 1; Press. Gas; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
mono-methylamine;mono-methylamine ... %	200-820-0	74-89-5	Flam. Liq. 1; Acute Tox. 4; Skin Corr. 1B
mono-2-[2-(4-dibenzo[b, f][1,4]thiazepin-11-yl)piperazinium-1-yl]ethoxy)ethanol trans-butenedioate ICI204636 HYDROGEN FUMARATE	415-180-1	773058-82-5	Acute Tox. 4; Eye Dam. 1
Monkeypox virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
molybdenum trioxide	215-204-7	1313-27-5	Carc. 2; Eye Irrit. 2; STOT SE 3
molybdenum nickel tetraoxide	238-034-5	14177-55-0	Carc. 1A; STOT RE 1; Skin Sens. 1
molybdenum nickel oxide	-	12673-58-4	Carc. 1A; STOT RE 1; Skin Sens. 1
molybdenum nickel hydroxide oxide phosphate	268-585-7	68130-36-9	Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
molinate (ISO);S-ethyl 1-perhydroazepinecarbothioate; S-ethyl perhydroazepine-1-carbothioate	218-661-0	2212-67-1	Carc. 2; Repr. 2; Acute Tox. 4; STOT RE 2; Skin Sens. 1
mixed linear and branched C14-15 alcohols ethoxylated, reaction product with epichlorohydrin NUPORE G45-10	420-480-9	158570-99-1	Skin Irrit. 2; Skin Sens. 1
mix-cresol	215-293-2	1319-77-3	Acute Tox. 3; Skin Corr. 1B
mipafox (ISO); N,N'-di-isopropylphosphorodiamidic fluoride	206-742-3	371-86-8	STOT SE 1
Mineral wool, with the exception of those specified elsewhere in this Annex [Man-made vitreous (silicate) fibres with random orientation with alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content greater than 18 % by weight] show/hide Glass, oxide, chemicals This category encompasses the various chemical substances manufactured in the production of inorganic glasses. For purposes of this category, 'glass' is defined as an amorfous, inorganic, transparent, translucent or opaque material traditionally formed by fusion of sources of silica with a flux, such as an alkali-metal carbonate, boron oxide, etc. and a stabilizer, into a mass which is cooled to a rigid condition without crystallization in the case of transparent or liquid-phase separated glass or with controlled crystallization in the case of glass-ceramics. The category consists of the various chemical substances, other than by-products or impurities, which are formed during the production of various glasses and concurrently incorporated into a glass mixture. All glasses contain one or more of these substances, but few, if any, contain all of them. The elements listed below are principally present as components of oxide systems but some may also be present as halides or chalcogenides, in multiple oxidation states, or in more complex compounds. Trace amounts of other oxides or chemical compounds may be present. Oxides of the first seven elements listed* comprise more than 95 percent, by weight, of the glass produced. @Aluminium@Lead@Boron@Lithium@Calcium@Manganese@Magnesium@Molybdenum@Potassium@Neodymium@Silicon@Nickel@Sodium*@Niobium@Antimony@Nitrogen@Arsenic@Phosphorus@Barium@Praseodymium@Bismuth@Rubidium@Cadmium@Selenium@Carbon@Silver@Cerium@Strontium@Cesium@Sulfur@Chromium@Tellurium@Cobalt@Tin@Copper@Titanium@Germanium@Tungsten@Gold@Uranium@Holmium@Vanadium@Iron@Zinc@Lanthanum@Zirconium EC / List no: 266-046-0 \| CAS no: 65997-17-3 Glass Wool EC / List no: - \| CAS no: 308066-92-4	-	-	Carc. 2
millerite	-	1314-04-1	Carc. 1A; Muta. 2; STOT RE 1; Skin Sens. 1
Milkers' node virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
milbemectin (ISO) [reaction mass of milbemycin A3 (CAS No 51596-10-2) and milbemycin A4 (CAS No 51596-11-3) (30:70)]	-	-	Acute Tox. 4
Microsporum spp.	-	-		F Fungi
mexacarbate (ISO); 3,5-dimethyl-4-dimethylaminophenyl N-methylcarbamate	206-249-3	315-18-4	Acute Tox. 2; Acute Tox. 4
mevinphos (ISO); 2-methoxycarbonyl-1-methylvinyl dimethyl phosphate	232-095-1	7786-34-7	Acute Tox. 1; Acute Tox. 2
metribuzin (ISO); 4-amino-6-tert-butyl-3-methylthio-1,2,4-triazin-5(4H)-one; 4-amino-4,5-dihydro-6-(1,1-dimethylethyl)-3-methylthio-1,2,4-triazin-5-one	244-209-7	21087-64-9	Acute Tox. 4; STOT RE 2
metosulam (ISO); N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a] pyrimidine-2-sulfonamide	410-240-1	139528-85-1	Carc. 2; STOT RE 2
metolcarb (ISO); m-tolyl methylcarbamate; MTMC	214-446-0	1129-41-5	Acute Tox. 4
methyltriphenylphosphonium chloride METHYL-TPP-CHLORID; MTPP-CHLORID	418-400-2	1031-15-8	Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
methylmercuric chloride	204-064-2	115-09-3	Carc. 2; Repr. 1A; Lact.; Acute Tox. 2; STOT RE 1
methylhydrazine	200-471-4	60-34-4	Carc. 1B
methylethylketone peroxide trimer	429-320-2	24748-23-0	Org. Perox. B; Asp. Tox. 1; Skin Irrit. 2; Skin Sens. 1
methylenediphenyl diisocyanate	247-714-0	26447-40-5	Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
methylene dithiocyanate	228-652-3	6317-18-6	Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
methylcyclohexane	203-624-3	108-87-2	Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
methyl-phenylene diamine	246-910-3	25376-45-8	Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Sens. 1
methyl-ONN-azoxymethyl acetate; methyl azoxy methyl acetate	209-765-7	592-62-1	Carc. 1B; Repr. 1B
methyl-5-nitrophenyl-guanidine	435-500-1	152460-07-6	Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
methyl-3-methoxyacrylate BETA-METHOXYACRYLSÄURE METHYLESTER	412-900-4	5788-17-0	Skin Sens. 1
methyl-2-[(aminosulfonyl)methyl]benzoate N 5297	419-010-5	112941-26-1	Acute Tox. 4; Eye Irrit. 2
methyl-2,3,5,6-tetrachloro-4- pyridylsulphone;2,3,5,6-tetrachloro-4-(methylsulphonyl)pyridine	236-035-5	13108-52-6	Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
methyl α-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-o-toluate F5384	401-340-6	83055-99-6	Skin Sens. 1
methyl vinyl ether	203-475-4	107-25-5	Flam. Gas 1; Press. Gas
methyl tetrahydro-2-furancarboxylate METHFAT	420-670-1	37443-42-8	Eye Dam. 1
methyl salicylate	204-317-7	119-36-8	Repr. 2; Acute Tox. 4; Skin Sens. 1B
methyl propionate	209-060-4	554-12-1	Flam. Liq. 2; Acute Tox. 4
methyl neodecanamide	414-460-9	105726-67-8	Acute Tox. 4
methyl N-[3-acetylamino)-4-(2-cyano-4-nitrophenylazo)phenyl]-N-[(1-methoxy)acetyl]glycinate FAT 40'489	413-040-2	149850-30-6	Skin Sens. 1
methyl N-(isopropoxycarbonyl)-L-valyl-(3RS)-3-(4-chlorophenyl)-β-alaninate; valifenalate	608-192-3	283159-90-0	Carc. 2
methyl methacrylate; methyl 2-methylprop-2-enoate; methyl 2-methylpropenoate	201-297-1	80-62-6	Flam. Liq. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
methyl isothiocyanate	209-132-5	556-61-6	Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
methyl isocyanate	210-866-3	624-83-9	Flam. Liq. 2; Repr. 2; Acute Tox. 2; Acute Tox. 3; Resp. Sens. 1; Skin Sens. 1; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
methyl iodide; iodomethane	200-819-5	74-88-4	Carc. 2; Acute Tox. 4; Acute Tox. 3; STOT SE 3; Skin Irrit. 2
methyl formate	203-481-7	107-31-3	Flam. Liq. 1; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
methyl chloroformate	201-187-3	79-22-1	Flam. Liq. 2; Acute Tox. 2; Acute Tox. 4; Skin Corr. 1B
methyl chloroacetate	202-501-1	96-34-4	Flam. Liq. 3; Acute Tox. 3; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
methyl acrylate; methyl propenoate	202-500-6	96-33-3	Flam. Liq. 2; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1
methyl acrylamidomethoxyacetate (containing ≥ 0,1 % acrylamid) MAGME 100 MONOMEER	401-890-7	77402-03-0	Carc. 1B; Muta. 1B; Acute Tox. 4; Eye Irrit. 2
methyl acrylamidoglycolate (containing ≥ 0,1 % acrylamide) MAGME(R) 200 MONOMER	403-230-3	77402-05-2	Carc. 1B; Muta. 1B; Skin Corr. 1B; Skin Sens. 1
methyl acetoacetate	203-299-8	105-45-3	Eye Irrit. 2
methyl acetate	201-185-2	79-20-9	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
methyl [2-(1,1-dimethylethyl)-6-methoxypyrimidin-4-yl]ethylphosphonothioate MAT 9460	414-080-3	117291-73-3	Acute Tox. 4
methyl 4-bromomethyl-3-methoxybenzoate BROMBENZOAT; BROMOBENZOATE	410-310-1	70264-94-7	Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
methyl 3-sulphamoyl-2-thenoate A5546	402-050-2	59337-93-8	Skin Sens. 1
methyl 3-isocyanatosulfonyl-2-thiophene-carboxylate F7641; MTSI	410-550-7	79277-18-2	STOT RE 2; Resp. Sens. 1; Skin Sens. 1
methyl 3-amino-4,6-dibromo-2-methyl-benzoate	425-190-6	119916-05-1	STOT RE 2
methyl 3-amino-2,2,3-trimethylbutyrate	431-720-7	90886-53-6	Skin Corr. 1B; Acute Tox. 4
methyl 3-[(dimethoxyphosphinothioyl)oxy]methacrylate	250-366-2	30864-28-9	Acute Tox. 4; Skin Sens. 1
methyl 3-(acetylthio)-2-methyl-propanoate D,L-ESTER	411-040-7	97101-46-7	Acute Tox. 4; Skin Sens. 1
methyl 3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate G 18-1108	403-270-1	6386-39-6	Acute Tox. 4
methyl 3,4-dichlorophenylcarbanilate; SWEP.	620-362-9	1918-18-9	Acute Tox. 4
methyl 2R,3S-(-)-3-(4-methoxyphenyl)oxiranecarboxylate MEFAT	404-130-2	105560-93-8	Eye Dam. 1; Skin Sens. 1
methyl 2-chlorosulfonyl-4-(methanesulfonylaminomethyl) benzoate	443-120-2	393509-79-0	Eye Dam. 1
methyl 2-benzylidene-3-oxobutyrate LUGALVAN ES 9571	420-940-9	15768-07-7	Eye Irrit. 2; Skin Irrit. 2
methyl 2-aminosulfonyl-6-(trifluoromethyl)pyridine-3-c arboxylate JE 127	421-220-7	144740-59-0	Skin Sens. 1
methyl 2-[4-(2-chloro-4-nitrophenylazo)-3-(1-oxopropyl)amino]phenylaminopropionate DISPERSE RED CLA 282	416-240-8	155522-12-6	Skin Sens. 1
methyl 2-(acetylamino)-3-chloropropionate	442-860-3	87333-22-0	Skin Sens. 1
methyl 2-(3-nitrobenzylidene)acetoacetate BM	405-270-7	39562-17-9	Skin Sens. 1
methyl 2-(2-nitrobenzylidene)acetoacetate 2-NITROBENZYLIDENE METHYL ESTER; BAY O 2787	400-650-9	39562-27-1	Skin Sens. 1
methyl 2,5-dichlorobenzoate	220-815-7	2905-69-3	Acute Tox. 4; STOT SE 3
methyl 2,2-dimethyl-6-methylenecyclohexanecarboxylate	432-350-9	81752-87-6	Skin Irrit. 2
methyl (±)-lactate;methyl lactate	208-930-0	2155-30-8;547-64-8	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
methyl (±)-lactate;methyl lactate	208-930-0	2155-30-8;547-64-8	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
methyl (S)-(-)-lactate	248-704-9	27871-49-4	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
methyl (R)-lactate	241-420-6	17392-83-5	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
methyl (R)-2-(4-hydroxyphenoxy)propionate DHPPME; MAK-ME; MEHPOPS; R-MAQ-ME	411-950-4	96562-58-2	Eye Dam. 1
methyl (R)-2-(4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy)propionate HALOXYFOP R-(+)-ME HERBICIDAL CHEMICAL	406-250-0	72619-32-0	Acute Tox. 4
methyl (9-acetoxy-3,8,10-triethyl-7,8,10-trimethyl-1,5-dioxa-9-aza-spiro[5.5]undec-3-yl)octadecanoate	445-990-9	376588-17-9	Skin Sens. 1
methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate GR138766X	415-670-3	78850-37-0	Eye Dam. 1
methoxyacetic acid	210-894-6	625-45-6	Repr. 1B; Acute Tox. 4; Skin Corr. 1B
methomyl (ISO); 1-(methylthio)ethylideneamino N-methylcarbamate	240-815-0	16752-77-5	Acute Tox. 2
methidathion (ISO); 2,3-dihydro-5-methoxy-2-oxo-1,3,4-thiadiazol-3-ylmethyl-O,O-dimethylphosphorodithioate	213-449-4	950-37-8	Acute Tox. 2; Acute Tox. 4
methenamine; hexamethylenetetramine	202-905-8	100-97-0	Flam. Sol. 2; Skin Sens. 1
methanol	200-659-6	67-56-1	Flam. Liq. 2; Acute Tox. 3; STOT SE 1
methanethiol; methyl mercaptan	200-822-1	74-93-1	Flam. Gas 1; Press. Gas; Acute Tox. 3
methanesulphonic acid	200-898-6	75-75-2	Skin Corr. 1B
methane	200-812-7	74-82-8	Flam. Gas 1; Press. Gas
methamidophos (ISO); O,S-dimethyl phosphoramidothioate	233-606-0	10265-92-6	Acute Tox. 2; Acute Tox. 3
methacrylonitrile; 2-methyl-2-propene nitrile	204-817-5	126-98-7	Flam. Liq. 2; Acute Tox. 3; Skin Sens. 1
methacrylic acid; 2-methylpropenoic acid	201-204-4	79-41-4	Acute Tox. 4; Skin Corr. 1A
methacrifos (ISO); methyl (E)-3-[(dimethoxyphosphinothioyl)oxy]methacrylate	630-448-8	62610-77-9	Acute Tox. 4; Skin Sens. 1
metconazole (ISO); (1RS, 5RS;1RS, 5SR)-5-(4-chlorobenzyl)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	603-031-3	125116-23-6	Repr. 2; Acute Tox. 4
metazachlor (ISO); 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)-acetamide	266-583-0	67129-08-2	Skin Sens. 1B; Carc. 2
metamitron (ISO);4-amino-3-methyl-6-phenyl-1,2,4-triazin-5-one	255-349-3	41394-05-2	Acute Tox. 4
metam-sodium (ISO); sodium methyldithiocarbamate	205-293-0	137-42-8	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
metalaxyl-M (ISO); mefenoxam; (R)-2-[(2,6-dimethylphenyl)-methoxyacetylamino]propionic acid methyl ester	615-135-6	70630-17-0	Acute Tox. 4; Eye Dam. 1
metalaxyl (ISO); methyl-N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-DL-alaninate	260-979-7	57837-19-1	Acute Tox. 4; Skin Sens. 1
metal salts of thiocyanic acid, with the exception of those specified elsewhere in this Annex	-	-	Acute Tox. 4
metaflumizone (ISO); (EZ)-2-[2-(4-cyanophe-nyl)-1-(a,a,a -trifluoro-m-tolyl)ethylidene]-[4-(tri-fluoromethoxy)phenyl] carbanilohydrazide [E-iso-mer > 90 %, Z-isomer <10 % relative content]	604-167-6	139968-49-3	Repr. 2; Lact.; STOT RE 2
metaflumizone (ISO); (E)-2-[2-(4-cyanophenyl)-1-(a,a,a -trifluoro-m-tolyl) ethylidene]-[4-(trifluoro-methoxy)phenyl]carbani-lohydrazide [2]	701-454-9	852403-68-0	Repr. 2; Lact.; STOT RE 2
mesotrione(ISO); 2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione	600-533-4	104206-82-8	Repr. 2; STOT RE 2
mesitylene; 1,3,5-trimethylbenzene	203-604-4	108-67-8	Flam. Liq. 3; STOT SE 3
mercury difulminate; mercuric fulminate; fulminate of mercury;mercury difulminate; mercuric fulminate; fulminate of mercury [≥ 20 % phlegmatiser]	211-057-8	628-86-4	Expl. 1.1; Acute Tox. 3; STOT RE 2
mercury difulminate; mercuric fulminate; fulminate of mercury;mercury difulminate; mercuric fulminate; fulminate of mercury [≥ 20 % phlegmatiser]	211-057-8	628-86-4	Unst. Expl.; Acute Tox. 3; STOT RE 2
mercury dichloride; mercuric chloride	231-299-8	7487-94-7	Muta. 2; Repr. 2; Acute Tox. 2; STOT RE 1; Skin Corr. 1B
mercury	231-106-7	7439-97-6	Repr. 1B; Acute Tox. 2; STOT RE 1
mercaptodimethur (ISO); methiocarb (ISO); 3,5-dimethyl-4-methylthiophenyl N-methylcarbamate	217-991-2	2032-65-7	Acute Tox. 3
mequinol; 4-methoxyphenol; hydroquinone monomethyl ether	205-769-8	150-76-5	Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
mepiquat chloride (ISO); 1,1-dimethylpiperidinium chloride	246-147-6	24307-26-4	Acute Tox. 4; Acute Tox. 3
mephosfolan (ISO); diethyl 4-methyl-1,3-dithiolan-2-ylidenephosphoramidate	213-447-3	950-10-7	Acute Tox. 1; Acute Tox. 2
mepanipyrim; 4-methyl-N-phenyl-6-(1-propynyl)-2-pyrimidinamine	432-140-7	110235-47-7	Carc. 2
menazon (ISO); S-[(4,6-diamino-1,3,5-triazin-2-yl)methyl] O, O-dimethyl phosphorodithioate	201-123-4	78-57-9	Acute Tox. 4
menadione sodium bisulfite; 2-naphthalenesulfonic acid,1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt	204-987-0	130-37-0	Eye Irrit. 2; Skin Irrit. 2
menadione nicotinamide bisulfite; 1,2,3,4-tetrahydro-2-methyl-1,4-dioxonaphthalene-2-sulfonicacid, compound with nicotin-3-amide (1:1)	277-543-7	73581-79-0	Eye Irrit. 2; Skin Irrit. 2
medinoterb acetate (ISO); 6-tert-butyl-3-methyl-2,4-dinitrophenyl acetate	219-634-6	2487-01-6	Acute Tox. 3; Acute Tox. 4
mecrilate; methyl 2-cyanoacrylate	205-275-2	137-05-3	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
mecoprop-P (ISO) and its salts; (R)-2-(4-chloro-2-methylphenoxy) propionic acid and its salts	-	-	Acute Tox. 4; Eye Dam. 1
mecetronium etilsulfate; N-ethyl-N,N-dimethylhexadecan-1-aminium ethyl sulfate; mecetronium ethyl sulphate; [MES]	221-106-5	3006-10-8	Skin Corr. 1; Eye Dam. 1
mecarbam (ISO); N-ethoxycarbonyl-N-methylcarbamoylmethyl O, O-diethyl phosphorodithioate	219-993-9	2595-54-2	Acute Tox. 3
Measles virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
MCPA-thioethyl (ISO); S-ethyl (4-chloro-2-methylphenoxy)ethanethioate; S-ethyl 4-chloro-o-tolyloxythioacetate	246-831-4	25319-90-8	Acute Tox. 4
MCPA (ISO); 4-chloro-o-tolyloxyacetic acid	202-360-6	94-74-6	Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
Mayaro virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Margosa, ext. [from the kernels of Azadirachta indica extracted with water and further processed with organic solvents] Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Azadirachta indica, Meliaceae.	283-644-7	84696-25-3	Repr. 2; Skin Sens. 1
Marburg virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Mansonella perstans	-	-		P Parasites
Mansonella ozzardi	-	-		P Parasites
mannitol hexanitrate; nitromannite;mannitol hexanitrate; nitromannite;[>40 % phlegmatiser]	239-924-6	15825-70-4	Expl. 1.1
mannitol hexanitrate; nitromannite;mannitol hexanitrate; nitromannite;[>40 % phlegmatiser]	239-924-6	15825-70-4	Unst. Expl.
manganese sulphate	232-089-9	7785-87-7	STOT RE 2
manganese dioxide	215-202-6	1313-13-9	Acute Tox. 4
maneb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric)	235-654-8	12427-38-2	Repr. 2; Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
mancozeb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric) complex with zinc salt	616-995-5	8018-01-7	Carc. 2; Repr. 1B; STOT RE 2; Skin Sens. 1
malononitrile	203-703-2	109-77-3	Acute Tox. 3
maleic anhydride	203-571-6	108-31-6	Acute Tox. 4; STOT RE 1; Skin Corr. 1B; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1A
maleic acid	203-742-5	110-16-7	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
malathion (ISO); 1,2-bis(ethoxycarbonyl)ethyl O, O-dimethyl phosphorodithioate [containing ≤ 0,03 % isomalathion]	204-497-7	121-75-5	Acute Tox. 4; Skin Sens. 1
malachite green oxalate	219-441-7	2437-29-8	Repr. 2; Acute Tox. 4; Eye Dam. 1
malachite green hydrochloride	209-322-8	569-64-2	Repr. 2; Acute Tox. 4; Eye Dam. 1
Main component: acetoacetic acid anilide/3-amino-1-hydroxybenzene (ATAN-MAP): trisodium {6-[(2 or 3 or 4)-amino-(4 or 5 or 6)-hydroxyphenylazo]-5'-(phenylsulfamoyl)-3-sulfonatonaphthalene-2-azobenzene-1,2'-diolato}-{6''-[1-(phenylcarbamoyl)ethylazo]-5'-(phenylsulfamoyl)-3-sulfonatonaphthalene-2''-azobenzene-1'',2'''-diolato}chromate (III); by-product 1: acetoacetic acid anilide/acetoacetic acid anilide (ATAN-ATAN): trisodium bis{6-[1-(phenylcarbamoyl)ethylazo]-5'''-(phenylsulfonyl)-3''-sulfonatonaphthalene-2-azobenzene-1,2'-diolato}chromate (III); by-product 2: 3-amino-1-hydroxybenzene/3-amino-1-hydroxybenzene (MAP-MAP): trisodium bis{6-[(2 or 3 or 4)-amino-(4 or 5 or 6)-hydroxyphenylazo]-5'-(phenylsulfamoyl)-3-sulfonatonaphthalene-2-azobenzene-1,2'-diolato}chromate (III) BLACK JR 578	419-230-1	-	Skin Sens. 1
main component 6 (isomer): asym. 1:2 Cr(III)-complex of: A: 3-hydroxy-4-(2-hydroxy-naphthalene-1-ylazo)naphthalene-1-sulfonic acid, Na-salt and B: 1-[2-hydroxy-5-(4-methoxy-phenylazo)phenylazo]naphthalene-2-ol; main component 8 (isomer):; asym. 1:2 Cr-complex of: A:; 3-hydroxy-4-(2-hydroxy-naphthalene-1-ylazo)-naphthalene-1-sulfonic acid, Na-salt and B: 1-[2-hydroxy-5-(4-methoxy-phenylazo)-phenylazo]-naphthalene-2-ol BLACK UL 1253	417-280-9	30785-74-1	Eye Dam. 1
main component 1 (isomer 1):; 2-{6-fluoro-4-[3-(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonapht-7-ylamino]-1,3,5-triazin-2-ylamino}-3-{6-fluoro-4-[3-(1,5-disulfonaphth-2-ylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt; main component 1 (isomer 2):; 2-{6-fluoro-4-[3-(2,5-disulfophenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-3-{6-fluoro-4-[3(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt; main component 2: 2,3-bis-{6-fluoro-4-[3-(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt; main component 3: 2,3-bis-{6-fluoro-4-[3-(1,5-disulfonaphth-2-ylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt	422-610-1	-	Eye Dam. 1
magnesium sodium fluoride silicate	442-650-1	56450-90-9	STOT RE 2
magnesium powder (pyrophoric);magnesium, powder or turnings	231-104-6	7439-95-4	Flam. Sol. 1; Water-react. 2; Self-heat. 1
magnesium powder (pyrophoric);magnesium, powder or turnings	231-104-6	7439-95-4	Water-react. 1; Pyr. Sol. 1
magnesium phosphide; trimagnesium diphosphide	235-023-7	12057-74-8	Water-react. 1; Acute Tox. 2; Acute Tox. 3; Acute Tox. 1
magnesium hexafluorosilicate	241-022-2	16949-65-8	Acute Tox. 3
magnesium bis((R)-2-(2,4-dichlorophenoxy)propionate) DUPLOSAN-DP-MAGNESIUM	413-360-2	164058-21-3	Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
magnesium alkyls	-	-	Pyr. Liq. 1; Water-react. 1; Skin Corr. 1B
Madurella mycetomatis	-	-		F Fungi
Madurella grisea	-	-		F Fungi
Machupo virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
m-xylene	203-576-3	108-38-3	Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2
m-tolylidene diisocyanate; toluene-diisocyanate	247-722-4	26471-62-5	Carc. 2; Acute Tox. 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
m-toluidine; 3-aminotoluene	203-583-1	108-44-1	Acute Tox. 3; STOT RE 2

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EU-SAFETY_HEALTH_WORK-PREAMBLE

EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

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Last updated 26 April 2024. Database contains 4691 unique substances/entries.

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