EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 26 April 2024. Database contains 4691 unique substances/entries.

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Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC
chlorthiamid (ISO); 2,6-dichloro (thiobenzamide)	217-637-7	1918-13-4	Acute Tox. 4
chlorthion O-(3-chloro-4-nitrophenyl) O, O-dimethyl phosphorothioate	207-902-5	500-28-7	Acute Tox. 4
chlorthiophos (ISO) [isomeric reaction mass in which O-2,5-dichlorophenyl-4-methylthiophenyl O, O-diethyl phosphorothioate predominates]	244-663-6	21923-23-9	Acute Tox. 2; Acute Tox. 3
chlozolinate (ISO); ethyl (RS)-3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-oxazolidine-5-carboxylate	282-714-4	84332-86-5	Carc. 2
chromium (VI) compounds, with the exception of barium chromate and of compounds specified elsewhere in this Annex	-	-	Carc. 1B; Skin Sens. 1
chromium (VI) trioxide	215-607-8	1333-82-0	Ox. Sol. 1; Carc. 1A; Muta. 1B; Repr. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Skin Corr. 1A; Resp. Sens. 1; Skin Sens. 1
chromyl dichloride; chromic oxychloride	239-056-8	14977-61-8	Ox. Liq. 1; Carc. 1B; Muta. 1B; Skin Corr. 1A; Skin Sens. 1
chrysene	205-923-4	218-01-9	Carc. 1B; Muta. 2
chrysoidine acetate; 4-(phenylazo)benzene-1,3-diamine acetate	279-116-0	79234-33-6	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine C10-14-alkyl derivatives; benzenesulfonic acid, mono-C10-14-alkyl derivatives, compounds; with 4-(phenylazo)-1,3-benzenediamine	286-946-7	85407-90-5	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine compound with dibutylnaphthalene sulfonic acid; dibutylnaphthalenesulfonic acid, compound with 4-(phenylazo)benzene-1,3-diamine (1:1)	304-236-8	94247-67-3	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine dihydrochloride; 4-(phenylazo)benzene-1,3-diamine dihydrochloride	281-549-5	83968-67-6	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine monoacetate; 4-(phenylazo)benzene-1,3-diamine monoacetate	278-290-5	75660-25-2	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine monohydrochloride; 4-phenylazophenylene-1,3-diamine monohydrochloride	208-545-8	532-82-1	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine sulfate; bis[4-(phenylazo)benzene-1,3-diamine] sulfate	282-432-1	84196-22-5	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine-p-dodecylbenzenesulfonate; dodecylbenzenesulfonic acid, compound with 4-(phenylazo)benzene-1,3-diamine (1:1)	264-409-8	63681-54-9	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine; 4-(phenylazo)benzene-1,3-diamine	207-803-7	495-54-5	Muta. 2; Acute Tox. 4; Skin Irrit. 2
chymotrypsin	232-671-2	9004-07-3	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
cinerin I; 3-(but-2-enyl)-2-methyl-4- oxocyclopent-2-enyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate	246-948-0	25402-06-6	Acute Tox. 4
cinerin II; 3-(but-2-enyl)-2-methyl-4- oxocyclopent-2-enyl 2,2-dimethyl-3-(3-methoxy-2-methyl-3-oxoprop-1-enyl)cyclopropanecarboxylate	204-454-2	121-20-0	Acute Tox. 4
cinidon ethyl (ISO); ethyl (Z)-2-chloro-3-[2-chloro-5-(cyclohex-1-ene-1,2-dicarboximido)phenyl]acrylate	604-318-6	142891-20-1	Carc. 2; Skin Sens. 1
cinmethylin (ISO); exo-(±)-1-methyl-2-(2-methylbenzyloxy)-4-isopropyl-7-oxabicyclo(2.2.1)heptane ARGOLD; CINMETHYLIN; WL 95481	402-410-9	87818-31-3	Acute Tox. 4
cinnamaldehyde; 3-phenylprop-2-enal; cinnamic aldehyde; cinnamal	203-213-9	104-55-2	Skin Sens. 1A
cis-1,2,3,6-tetrahydro-4-methylphthalic anhydride	216-906-6	1694-82-2	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
cis-1,2,3,6-tetrahydrophthalicanhydride	213-308-7	935-79-5	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
cis-1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinamine	425-080-8	104860-26-6	Acute Tox. 4; STOT RE 2; Eye Dam. 1
cis-1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride	426-020-3	51229-78-8	Flam. Sol. 2; Repr. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
cis-1-(3-chloropropyl)-2,6-dimethyl-piperidin hydrochloride PD 133602-2	417-430-3	63645-17-0	Acute Tox. 3; STOT RE 2; Skin Sens. 1
cis-1-amino-2,3-dihydro-1H-inden-2-ol	422-660-2	7480-35-5	Eye Dam. 1; Skin Sens. 1
cis-2-methylcyclohexanol	231-187-9	7443-70-1	Acute Tox. 4
cis-cyclohexane-1,2-dicarboxylicanhydride	236-086-3	13149-00-3	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
cis-dichloroethylene	205-859-7	156-59-2	Flam. Liq. 2; Acute Tox. 4
citral	226-394-6	5392-40-5	Skin Irrit. 2; Skin Sens. 1
citric acid	201-069-1	77-92-9	Eye Irrit. 2; STOT SE 3
citric acid, ammonium nickel salt	242-161-1	18283-82-4	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
citric acid, nickel salt	245-119-0	22605-92-1	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
Cladophialophora bantiana	-	-		F Fungi
Clarified oils (petroleum), catalytic cracked; Heavy Fuel oil [A complex combination of hydrocarbons produced as the residual fraction from distillation of the products from a catalytic cracking process. It consists of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350°C (662°F). This stream is likely to contain 5 wt. % or more of 4-to 6-membered condensed ring aromatic hydrocarbons.] A complex combination of hydrocarbons produced as the residual fraction from distillation of the products from a catalytic cracking process. It consists of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350°C (662°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.	265-064-6	64741-62-4	Carc. 1B
Clarified oils (petroleum), hydrodesulfurized catalytic cracked; Heavy Fuel oil [A complex combination of hydrocarbons obtained by treating catalytic cracked clarified oil with hydrogen to convert organic sulfur to hydrogen sulfide which is removed. It consists of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350 °C (662 °F). This stream is likely to contain 5 wt. % or more of 4-to 6-membered condensed ring aromatic hydrocarbons.] A complex combination of hydrocarbons obtained by treating catalytic cracked clarified oil with hydrogen to convert organic sulfur to hydrogen sulfide which is removed. It consists of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350°C (662°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.	269-782-0	68333-26-6	Carc. 1B
clethodim (ISO); (5RS)-2-{(1EZ)-1-[(2E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylthio)propyl]-3-hydroxycyclohex-2-en-1-one	619-396-7	99129-21-2	Acute Tox. 4; Skin Sens. 1
clodinafop-propargyl (ISO)	600-662-6	105512-06-9	Acute Tox. 4; STOT RE 2; Skin Sens. 1
clomazone (ISO); 2-(2-chlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one	617-258-0	81777-89-1	Acute Tox. 4
Clonorchis sinensis	-	-		P Parasites
Clonorchisviverrini	-	-		P Parasites
clopyralid (ISO); 3,6-dichloropyridine-2-carboxylic acid	216-935-4	1702-17-6	Eye Dam. 1
clorofene; chlorophene; 2-benzyl-4-chlorophenol	204-385-8	120-32-1	Carc. 2; Repr. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1; Eye Dam. 1; STOT RE 2
Clostridium botulinum	-	-		B Bacteria and similar species
Clostridium perfringens	-	-		B Bacteria and similar species
Clostridium spp.	-	-		B Bacteria and similar species
Clostridium tetani	-	-		B Bacteria and similar species
clothianidin (ISO); (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine	433-460-1	210880-92-5	Repr. 2; Acute Tox. 4; STOT SE 1
Coal liquids, liq. solvent extn. [The substantially solvent-free product obtained by the distillation of the solvent from filtered coal extract solution produced by digesting coal in a liquid solvent. A black semi-solid, composed primarily of a complex combination of condensed-ring aromatic hydrocarbons, aromatic nitrogen compounds, aromatic sulfur compounds, phenolic compounds and other aromatic oxygen compounds, and their alkyl derivatives.] The substantially solvent-free product obtained by the distillation of the solvent from filtered coal extract solution produced by digesting coal in a liquid solvent. A black semi-solid, composed primarily of a complex combination of condensed-ring aromatic hydrocarbons, aromatic nitrogen compounds, aromatic sulfur compounds, phenolic compounds and other aromatic oxygen compounds, and their alkyl derivatives.	302-683-3	94114-48-4	Carc. 1B
Coal liquids, liq. solvent extn. soln. [The product obtained by filtration of coal mineral matter and undissolved coal from coal extract solution produced by digesting coal in a liquid solvent. A black, viscous, highly complex liquid combination composed primarily of aromatic and partly hydro-genated aromatic hydrocarbons, aromatic nitrogen compounds, aromatic sulfur compounds, phenolic and other aromatic oxygen compounds and their alkyl derivatives.] The product obtained by filtration of coal mineral matter and undissolved coal from coal extract solution produced by digesting coal in a liquid solvent. A black, viscous, highly complex liquid combination composed primarily of aromatic and partly hydrogenated aromatic hydrocarbons, aromatic nitrogen compounds, aromatic sulfur compounds, phenolic and other aromatic oxygen compounds and their alkyl derivatives.	302-682-8	94114-47-3	Carc. 1B
cobalt	231-158-0	7440-48-4	Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1
cobalt carbonate	208-169-4	513-79-1	Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1
cobalt di(acetate)	200-755-8	71-48-7	Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1
cobalt dichloride	231-589-4	7646-79-9	Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1
cobalt dimolybdenum nickel octaoxide	268-169-5	68016-03-5	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt dinitrate	233-402-1	10141-05-6	Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1
cobalt lithium nickel oxide	442-750-5	113066-89-0	Carc. 1A; Acute Tox. 2; STOT RE 1; Skin Sens. 1
cobalt nickel dioxide	261-346-8	58591-45-0	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt nickel gray periclase; C.I. Pigment Black 25; C.I. 77332 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77332.	269-051-6	68186-89-0	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt nickel oxide	620-395-9	12737-30-3	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt oxide	215-154-6	1307-96-6	Acute Tox. 4; Skin Sens. 1
cobalt sulfate	233-334-2	10124-43-3	Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1
cobalt sulfide	215-273-3	1317-42-6	Skin Sens. 1
Coccidioides inunitis	-	-		F Fungi
colchicine	200-598-5	64-86-8	Muta. 1B; Acute Tox. 2
colecalciferol; cholecalciferol; Vitamin D3	200-673-2	67-97-0	Acute Tox. 2; STOT RE 1
Coltivirus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
complex of cobalt(III)-bis(N-phenyl-4-(5-ethylsulfonyl-2-hydroxyphenylazo)-3-hydroxynaphthylamide), hydrated(n H2O,2 SUBSTANCE S171393	427-390-9	-	Skin Sens. 1
condensation product of: 3-(7-carboxyhept-1-yl)-6-hexyl-4-cyclohexene-1,2-dicarboxylic acid with polyamines (primarily; amino-ethyl-piperazine and triethylenetetramine) INDULIN MQK-1M	413-770-1	-	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
constitutional isomers of penta-O-allyl-β-D-fructofuranosyl-α-D-glucopyranoside; constitutional isomers of hexa-O-allyl-β-D-fructofuranosyl-α-D-glucopyranoside; constitutional isomers of hepta-O-allyl-β-D-fructofuransoyl-α-D-glucopyranoside ALLYL SUCROSE	419-640-0	68784-14-5	Acute Tox. 4
copper chloride; copper (I) chloride; cuprous chloride	231-842-9	7758-89-6	Acute Tox. 4
copper dihydroxide; copper(II) hydroxide	243-815-9	20427-59-2	Acute Tox. 2; Acute Tox. 4; Eye Dam. 1
copper flakes (coated with aliphatic acid)	-	-	Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2
copper sulphate	231-847-6	7758-98-7	Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
copper sulphate pentahydrate	616-477-9	7758-99-8	Acute Tox. 4; Eye Dam. 1
copper(II) carbonate-copper(II) hydroxide (1:1)	235-113-6	12069-69-1	Acute Tox. 4; Eye Irrit. 2
copper(II) methanesulfonate KUPFER-II-METHANSULFONAT; KUPFERMETHANSULFONAT	405-400-2	54253-62-2	Acute Tox. 4; Eye Dam. 1
coriandrol; (S)-3,7-dimethyl-1,6-octadien-3-ol; d-linalool	204-810-7	126-90-9	Skin Sens. 1B
Coronaviridae	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Corynebacterium diphtheriae	-	-		B Bacteria and similar species
Corynebacterium minutissimum	-	-		B Bacteria and similar species
Corynebacterium pseudotuberculosis	-	68583-16-4		B Bacteria and similar species
Corynebacterium spp.	-	-		B Bacteria and similar species
coumachlor (ISO); 3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxycoumarin	201-378-1	81-82-3	STOT RE 2
coumafuryl (ISO); fumarin; (RS)-3-(1-(2-furyl)-3-oxobutyl)4-hydroxycoumarin; 4-hydroxy-3-[3-oxo-1-(2-furyl)butyl]coumarin	204-195-5	117-52-2	Acute Tox. 3; STOT RE 1
coumaphos (ISO); O-3-chloro-4-methylcoumarin-7-yl O,O-diethyl phosphorothioate	200-285-3	56-72-4	Acute Tox. 2; Acute Tox. 4
coumatetralyl; 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin	227-424-0	5836-29-3	Repr. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1
coumithoate (ISO); O,O-diethyl O-7,8,9,10-tetrahydro-6-oxo-benzo(c)chromen-3-yl phosphorothioate	-	572-48-5	Acute Tox. 3
Cowpox virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Coxiella burnetii	-	-		B Bacteria and similar species
Coxsackie viruses	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Creosote [The distillate of coal tar produced by the high temperature carbonization of bituminous coal. It consists primarily of aromatic hydrocarbons, tar acids and tar bases.] The distillate of coal tar produced by the high temperature carbonization of bituminous coal. It consists primarily of aromatic hydrocarbons, tar acids and tar bases.	232-287-5	8001-58-9	Carc. 1B
Creosote oil [A complex combination of hydrocarbons obtained by the distillation of coal tar. It consists primarily of aromatic hydrocarbons and may contain appreciable quantities of tar acids and tar bases. It distills at the approximate range of 200 °C to 325 °C (392°F to 617°F).] A complex combination of hydrocarbons obtained by the distillation of coal tar. It consists primarily of aromatic hydrocarbons and may contain appreciable quantities of tar acids and tar bases. It distills at the approximate range of 200°C to 325°C (392°F to 617°F).	263-047-8	61789-28-4	Carc. 1B
Creosote oil, acenaphthene fraction, acenaphthene-free; Wash Oil Redistillate [The oil remaining after removal by a crystallization process of acenaphthene from acenaphthene oil from coal tar. Composed primarily of naphthalene and alkylnaphthalenes.] The oil remaining after removal by a crystallization process of acenaphthene from acenaphthene oil from coal tar. Composed primarily of naphthalene and alkylnaphthalenes.	292-606-9	90640-85-0	Carc. 1B
Creosote oil, acenaphthene fraction; Wash Oil [A complex combination of hydrocarbons produced by the distillation of coal tar and boiling in the range of approximately 240 o C to 280 o C (464°F to 536 °F). Composed primarily of acenaphthene, naphthalene and alkyl naphthalene.] A complex combination of hydrocarbons produced by the distillation of coal tar and boiling in the range of approximately 240°C to 280°C (464°F to 536°F). Composed primarily of acenaphthene, naphthalene and alkyl naphthalene.	292-605-3	90640-84-9	Carc. 1B
Creosote oil, high-boiling distillate; Wash Oil [The high-boiling distillation fraction obtained from the high temperature carbonization of bituminous coal which is further refined to remove excess crystalline salts. It consists primarily of creosote oil with some of the normal polynuclear aromatic salts, which are components of coal tar distillates, removed. It is crystal free at approximately 5 °C (41°F).] The high-boiling distillation fraction obtained from the high temperature carbonization of bituminous coal which is further refined to remove excess crystalline salts. It consists primarily of creosote oil with some of the normal polynuclear aromatic salts, which are components of coal tar distillates, removed. It is crystal free at approximately 5°C (41°F).	274-565-9	70321-79-8	Carc. 1B
Creosote oil, low-boiling distillate; Wash Oil [The low-boiling distillation fraction obtained from the high temperature carbonization of bituminous coal, which is further refined to remove excess crystalline salts. It consists primarily of creosote oil with some of the normal polynuclear aromatic salts, which are components of coal tar distillate, removed. It is crystal free at approximately 38 o C (100 oF).] The low-boiling distillation fraction obtained from the high temperature carbonization of bituminous coal, which is further refined to remove excess crystalline salts. It consists primarily of creosote oil with some of the normal polynuclear aromatic salts, which are components of coal tar distillate, removed. It is crystal free at approximately 38°C (100°F).	274-566-4	70321-80-1	Carc. 1B
Creutzfeldt-Jakob disease	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Crimean-Congo haemorrhagic fever	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
crimidine (ISO);2-chloro-6-methylpyrimidin-4- yldimethylamine	208-622-6	535-89-7	Acute Tox. 2
crotonaldehyde; 2-butenal	224-030-0	4170-30-3	Flam. Liq. 2; Muta. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
crotoxyphos (ISO); 1-phenylethyl 3-(dimethoxyphosphinyloxy) isocrotonate	231-720-5	7700-17-6	Acute Tox. 3
crufomate (ISO); 4-tert-butyl-2-chlorophenyl methyl methylphosphoramidate	206-083-1	299-86-5	Acute Tox. 4
Cryptococcus neoformans var. gattii	-	-		F Fungi
Cryptococcus neoformans var. neofonnans	-	-		F Fungi
Cryptosporidium parvum	-	-		P Parasites
Cryptosporidium spp.	-	-		P Parasites
cumene	202-704-5	98-82-8	Flam. Liq. 3; Carc. 1B; Asp. Tox. 1; STOT SE 3
cyanamide; carbanonitril	206-992-3	420-04-2	Carc. 2; Repr. 2; Acute Tox. 3; STOT RE 2; Skin Corr. 1; Skin Sens. 1; Eye Dam. 1
cyanazine (ISO);2-(4-chloro-6-ethylamino-1,3,5- triazine-2-ylamino)-2-methylpropionitrile	244-544-9	21725-46-2	Acute Tox. 4
cyanofenphos (ISO); O-4-cyanophenyl O-ethyl phenylphosphonothioate	620-377-0	13067-93-1	Acute Tox. 3; STOT SE 1; Acute Tox. 4; Eye Irrit. 2
cyanophos (ISO); O-4-cyanophenyl O,O-dimethyl phosphorothioate	220-130-3	2636-26-2	Acute Tox. 4
cyanthoate (ISO); S-(N-(1-cyano-1-methylethyl)carbamoylmethyl) O,O-diethyl phosphorothioate	223-099-4	3734-95-0	Acute Tox. 2; Acute Tox. 3
cyclanilide (ISO); 1-(2,4-dichloroanilinocarbonyl)cyclopropanecarboxylic acid CSDCA	419-150-7	113136-77-9	Acute Tox. 4
cyclic 3-(1,2-ethanediylacetale)-estra-5(10),9(11)-diene-3,17-dione	427-230-8	5571-36-8	Repr. 1B; STOT RE 2
cyclohexadeca-1,9-diene	431-730-1	4277-06-9	Skin Irrit. 2; Skin Sens. 1
cyclohexane	203-806-2	110-82-7	Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
cyclohexane-1,2-dicarboxylic anhydride	201-604-9	85-42-7	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
cyclohexanol	203-630-6	108-93-0	Acute Tox. 4; STOT SE 3; Skin Irrit. 2
cyclohexanone	203-631-1	108-94-1	Flam. Liq. 3; Acute Tox. 4
cyclohexanone, peroxide;cyclohexanone, peroxide [≤ 91 % solution]	235-527-7	12262-58-7	Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
cyclohexanone, peroxide;cyclohexanone, peroxide [≤ 91 % solution]	235-527-7	12262-58-7	Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
cycloheximide (ISO);4-{(2R)-2-[(1S,3S,5S)-3,5- dimethyl-2-oxocyclohexyl]-2- hydroxyethyl}piperidine-2,6- dione	200-636-0	66-81-9	Muta. 2; Repr. 1B; Acute Tox. 2
cyclohexyl acrylate	221-319-3	3066-71-5	STOT SE 3; Skin Irrit. 2
cyclohexylamine	203-629-0	108-91-8	Flam. Liq. 3; Repr. 2; Acute Tox. 4; Skin Corr. 1B
cyclohexyldimethoxymethylsilane CHMMS; CHMS; DYNASYLAN 9407; Z-6187	402-140-1	17865-32-6	Skin Irrit. 2
cyclohexylidene hydroperoxide;cyclohexylidene hydroperoxide [≤ 91 % solution]	220-279-4	2699-11-8	Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
cyclohexylidene hydroperoxide;cyclohexylidene hydroperoxide [≤ 91 % solution]	220-279-4	2699-11-8	Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
cyclooct-4-en-1-yl methyl carbonate VIOLIFF	401-620-8	87731-18-8	Skin Sens. 1
cyclopentane	206-016-6	287-92-3	Flam. Liq. 2
cyclopentane-1,2,3,4-tetracarboxylic dianhydride	227-964-7	6053-68-5	Eye Irrit. 2; STOT SE 3
cyclopentanone	204-435-9	120-92-3	Flam. Liq. 3; Eye Irrit. 2; Skin Irrit. 2
cyclopentyl 2-phenylethyl ether	428-340-9	238088-70-5	Skin Irrit. 2
cyclopentyl chloroformate CHLOROFORMIATE DE CYCLOPENTYLE; CYCLOPENTYLCHLORFORMIAT	411-460-0	50715-28-1	Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
cyclopropane	200-847-8	75-19-4	Flam. Gas 1; Press. Gas
Cyclospora cayetanensis	-	-		P Parasites
cycloxydim (ISO); 2-(N-ethoxybutanimidoyl)-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	405-230-9	101205-02-1	Repr. 2
cyflumetofen (ISO); 2-methoxyethyl (RS)-2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-(α,α,α-trifluoro-o-tolyl)propionate	642-974-5	400882-07-7	Carc. 2; Skin Sens. 1A
cyfluthrin (ISO); α-cyano-4-fluoro-3-phenoxybenzyl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	269-855-7	68359-37-5	Lact.; Acute Tox. 2; STOT SE 1
cyhexatin (ISO); hydroxytricyclohexylstannane; tri(cyclohexyl)tin hydroxide	236-049-1	13121-70-5	Acute Tox. 4
cymoxanil (ISO); 2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide	261-043-0	57966-95-7	Repr. 2; Acute Tox. 4; STOT RE 2; Skin Sens. 1
cypermethrin (ISO); α-cyano-3-phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; cypermethrin cis/trans +/- 40/60;cypermethrin cis/trans +/-80/20; (RS)-α-cyano-3-phenoxybenzyl (1RS;3RS; 1RS, 3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	257-842-9	52315-07-8	Acute Tox. 4; STOT SE 3; STOT RE 2
cypermethrin (ISO); α-cyano-3-phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; cypermethrin cis/trans +/- 40/60;cypermethrin cis/trans +/-80/20; (RS)-α-cyano-3-phenoxybenzyl (1RS;3RS; 1RS, 3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	257-842-9	52315-07-8	Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
cyproconazole (ISO); (2RS,3RS;2RS,3SR)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl) butan-2-ol	619-020-1	94361-06-5	Repr. 1B; Acute Tox. 3; STOT RE 2
cyprodinil (ISO); 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	601-785-8	121552-61-2	Skin Sens. 1
cyprofuram (ISO); N-(3-chlorophenyl)-N-(tetrahydro-2-oxo-3-furyl)cyclopropanecarboxamide	274-050-9	69581-33-5	Acute Tox. 3; Acute Tox. 4
Cytomegalovirus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
D, L-(N,N-diethyl-2-hydroxy-2-phenylacetamide) DEM	408-120-9	65197-96-8	Acute Tox. 4; Eye Dam. 1
d-carvone; (5S)-2-methyl-5- (prop-1-en-2-yl)cyclohex-2-en- 1-one	218-827-2	2244-16-8	Skin Sens. 1
D-erythro-hexanoic acid 2,4-dideoxy-3,5-O-(1-methylethylidene)-1,1-dimethylethylester; tert-butyl 2-[(4R, 6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate	432-960-5	124655-09-0	Acute Tox. 4
dalapon-sodium; sodium 2,2-dichloropropionate	204-828-5	127-20-8	Skin Irrit. 2; Eye Dam. 1
dalapon; 2,2-dichloropropionic acid	200-923-0	75-99-0	Skin Irrit. 2; Eye Dam. 1
daminozide (ISO); 4-(2,2-dimethylhydrazino)-4-oxobutanoic acid; N-dimethylaminosuccinamic acid	216-485-9	1596-84-5	Carc. 2
dapsone; 4,4'-diamino diphenyl sulfone	201-248-4	80-08-0	Acute Tox. 4
dazomet (ISO);tetrahydro-3,5-dimethyl-1,3,5- thiadiazine-2-thione	208-576-7	533-74-4	Acute Tox. 4; Eye Irrit. 2
DDT (ISO); clofenotane (INN); dicophane;1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane; dichlorodiphenyltrichloroethane	200-024-3	50-29-3	Carc. 2; Acute Tox. 3; STOT RE 1
decanoic acid	206-376-4	334-48-5	Skin Irrit. 2; Eye Irrit. 2
decarbofuran (ISO); 2,3-dihydro-2-methylbenzofuran-7-yl methylcarbamate	-	1563-67-3	Acute Tox. 3
deltamethrin (ISO); (S)-α-cyano-3-phenoxybenzyl(1R, 3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate	258-256-6	52918-63-5	Acute Tox. 3
demephion-O (ISO); O, O-dimethyl O-2-methylthioethyl phosphorothioate	211-666-9	682-80-4	Acute Tox. 2; Acute Tox. 3
demephion-S (ISO); O, O-dimethyl S-2-methylthioethyl phosphorothioate	219-971-9	2587-90-8	Acute Tox. 2; Acute Tox. 3
demeton	620-378-6	8065-48-3	Acute Tox. 1; Acute Tox. 2
demeton-O (ISO); O,O-diethyl-O-2-ethylthioethyl phosphorothioate	206-053-8	298-03-3	Acute Tox. 1; Acute Tox. 2
demeton-O-methyl (ISO); O-2-ethylthioethyl O,O-dimethyl phosphorothioate	212-758-1	867-27-6	Acute Tox. 3
demeton-S (ISO); diethyl-S-2-ethylthioethyl phosphorothioate	204-801-8	126-75-0	Acute Tox. 1; Acute Tox. 2
demeton-S-methyl (ISO); S-2-ethylthioethyl dimethyl phosphorothioate	213-052-6	919-86-8	Acute Tox. 3
demeton-S-methylsulphon(ISO); S-2-ethylsulphonylethyl dimethyl phosphorothioate	241-109-5	17040-19-6	Acute Tox. 3; Acute Tox. 4
Dengue virus type 1-4	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate	237-198-5	13684-56-5	Repr. 2
desmetryne (ISO);6-isopropylamino-2-methylamino-4-methylthio-1,3,5- triazine	213-800-1	1014-69-3	Acute Tox. 4
di(benzothiazol-2-yl) disulphide	204-424-9	120-78-5	Skin Sens. 1
di(tetramethylammonium)(29H,31H-phthalocyanin-N29,N30,N31,N32)disulfonamide disulfonate, cuprate(2-)complex, derivates DIRECT BLUE 199	416-180-2	12222-04-7	Acute Tox. 4; STOT RE 2
di-allate (ISO); S-(2,3-dichloroallyl)-N,N-diisopropylthiocarbamate	218-961-1	2303-16-4	Carc. 2; Acute Tox. 4
di-L-para-menthene PINOLENE	417-870-6	83648-84-4	Skin Irrit. 2; Skin Sens. 1
di-L-para-menthene	686-814-2	34363-01-4	Skin Irrit. 2; Skin Sens. 1
di-methylamine;di-methylamine ... %	204-697-4	124-40-3	Flam. Liq. 1; Acute Tox. 4; Skin Corr. 1B
di-methylamine;di-methylamine ... %	204-697-4	124-40-3	Flam. Gas 1; Press. Gas; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
di-n-butyl ether; dibutyl ether	205-575-3	142-96-1	Flam. Liq. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
di-n-butylamine	203-921-8	111-92-2	Flam. Liq. 3; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Eye Dam. 1
di-n-octylaluminium iodide DNOAI	408-190-0	7585-14-0	Pyr. Liq. 1; Skin Corr. 1B
di-n-pentyl phthalate	205-017-9	131-18-0	Repr. 1B
di-tert-(C12-14)-alkylammonium 2-benzothiazolylthiosuccinate CM 26-137	406-052-4	125078-60-6	Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
di-tert-butyl peroxide	203-733-6	110-05-4	Org. Perox. E; Flam. Liq. 2; Muta. 2
dialifos (ISO); 2-chloro-1-phthalimidoethyl O,O-diethyl phosphorodithioate	233-689-3	10311-84-9	Acute Tox. 2; Acute Tox. 3
diallyl phthalate	205-016-3	131-17-9	Acute Tox. 4
dialuminium nickel tetraoxide	234-454-8	12004-35-2	Carc. 1A; STOT RE 1; Skin Sens. 1
diaminotoluene [technical product — reaction mass of 4-methyl-m-phenylene diamine (EC No 202-453-1) and 2-methyl-m-phenylene diamine (EC No 212-513-9)]	-	-	Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Sens. 1
diamminediisocyanatozinc GENIPLEX A	401-610-3	122012-52-6	Acute Tox. 4; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
diammonium 1-hydroxy-2-(4-(4-carboxyphenylazo)-2,5-dimethoxyphenylazo)-7-amino-3-naphthalenesulfonate	422-670-7	150202-11-2	Repr. 2; Acute Tox. 3; STOT RE 2
diammonium hexachloroplatinate	240-973-0	16919-58-7	Acute Tox. 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
diammonium nickel bis(sulfate)	239-793-5	15699-18-0	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1
diammonium nickel hexacyanoferrate	-	74195-78-1	Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
diammonium peroxodisulphate; ammonium persulphate	231-786-5	7727-54-0	Ox. Sol. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
diammonium tetrachloroplatinate	237-499-1	13820-41-2	Acute Tox. 3; Skin Irrit. 2; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
diarsenic pentaoxide; arsenic pentoxide; arsenic oxide	215-116-9	1303-28-2	Carc. 1A; Acute Tox. 3
diarsenic trioxide; arsenic trioxide	215-481-4	1327-53-3	Carc. 1A; Acute Tox. 2; Skin Corr. 1B
diazinon (ISO); O,O-diethyl O-2-isopropyl-6-methylpyrimidin-4-yl phosphorothioate	206-373-8	333-41-5	Acute Tox. 4

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EU-SAFETY_HEALTH_WORK-PREAMBLE

EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

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Last updated 26 April 2024. Database contains 4691 unique substances/entries.

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