EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 26 April 2024. Database contains 4691 unique substances/entries.
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V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
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V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
208-622-6
535-89-7
Acute Tox. 2
224-030-0
4170-30-3
Flam. Liq. 2; Muta. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
231-720-5
7700-17-6
Acute Tox. 3
206-083-1
299-86-5
Acute Tox. 4
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F Fungi
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F Fungi
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P Parasites
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P Parasites
202-704-5
98-82-8
Flam. Liq. 3; Carc. 1B; Asp. Tox. 1; STOT SE 3
206-992-3
420-04-2
Carc. 2; Repr. 2; Acute Tox. 3; STOT RE 2; Skin Corr. 1; Skin Sens. 1; Eye Dam. 1
244-544-9
21725-46-2
Acute Tox. 4
620-377-0
13067-93-1
Acute Tox. 3; STOT SE 1; Acute Tox. 4; Eye Irrit. 2
220-130-3
2636-26-2
Acute Tox. 4
223-099-4
3734-95-0
Acute Tox. 2; Acute Tox. 3
CSDCA
419-150-7
113136-77-9
Acute Tox. 4
427-230-8
5571-36-8
Repr. 1B; STOT RE 2
431-730-1
4277-06-9
Skin Irrit. 2; Skin Sens. 1
203-806-2
110-82-7
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
201-604-9
85-42-7
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
203-630-6
108-93-0
Acute Tox. 4; STOT SE 3; Skin Irrit. 2
203-631-1
108-94-1
Flam. Liq. 3; Acute Tox. 4
235-527-7
12262-58-7
Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
235-527-7
12262-58-7
Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
200-636-0
66-81-9
Muta. 2; Repr. 1B; Acute Tox. 2
221-319-3
3066-71-5
STOT SE 3; Skin Irrit. 2
203-629-0
108-91-8
Flam. Liq. 3; Repr. 2; Acute Tox. 4; Skin Corr. 1B
CHMMS; CHMS; DYNASYLAN 9407; Z-6187
402-140-1
17865-32-6
Skin Irrit. 2
220-279-4
2699-11-8
Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
220-279-4
2699-11-8
Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
VIOLIFF
401-620-8
87731-18-8
Skin Sens. 1
206-016-6
287-92-3
Flam. Liq. 2
227-964-7
6053-68-5
Eye Irrit. 2; STOT SE 3
204-435-9
120-92-3
Flam. Liq. 3; Eye Irrit. 2; Skin Irrit. 2
428-340-9
238088-70-5
Skin Irrit. 2
CHLOROFORMIATE DE CYCLOPENTYLE; CYCLOPENTYLCHLORFORMIAT
411-460-0
50715-28-1
Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
200-847-8
75-19-4
Flam. Gas 1; Press. Gas
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P Parasites
405-230-9
101205-02-1
Repr. 2
642-974-5
400882-07-7
Carc. 2; Skin Sens. 1A
269-855-7
68359-37-5
Lact.; Acute Tox. 2; STOT SE 1
236-049-1
13121-70-5
Acute Tox. 4
261-043-0
57966-95-7
Repr. 2; Acute Tox. 4; STOT RE 2; Skin Sens. 1
257-842-9
52315-07-8
Acute Tox. 4; STOT SE 3; STOT RE 2
257-842-9
52315-07-8
Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
619-020-1
94361-06-5
Repr. 1B; Acute Tox. 3; STOT RE 2
601-785-8
121552-61-2
Skin Sens. 1
274-050-9
69581-33-5
Acute Tox. 3; Acute Tox. 4
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V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
DEM
408-120-9
65197-96-8
Acute Tox. 4; Eye Dam. 1
218-827-2
2244-16-8
Skin Sens. 1
432-960-5
124655-09-0
Acute Tox. 4
204-828-5
127-20-8
Skin Irrit. 2; Eye Dam. 1
200-923-0
75-99-0
Skin Irrit. 2; Eye Dam. 1
216-485-9
1596-84-5
Carc. 2
201-248-4
80-08-0
Acute Tox. 4
208-576-7
533-74-4
Acute Tox. 4; Eye Irrit. 2
200-024-3
50-29-3
Carc. 2; Acute Tox. 3; STOT RE 1
206-376-4
334-48-5
Skin Irrit. 2; Eye Irrit. 2
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1563-67-3
Acute Tox. 3
258-256-6
52918-63-5
Acute Tox. 3
211-666-9
682-80-4
Acute Tox. 2; Acute Tox. 3
219-971-9
2587-90-8
Acute Tox. 2; Acute Tox. 3
620-378-6
8065-48-3
Acute Tox. 1; Acute Tox. 2
206-053-8
298-03-3
Acute Tox. 1; Acute Tox. 2
212-758-1
867-27-6
Acute Tox. 3
204-801-8
126-75-0
Acute Tox. 1; Acute Tox. 2
213-052-6
919-86-8
Acute Tox. 3
241-109-5
17040-19-6
Acute Tox. 3; Acute Tox. 4
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V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
237-198-5
13684-56-5
Repr. 2
213-800-1
1014-69-3
Acute Tox. 4
204-424-9
120-78-5
Skin Sens. 1
DIRECT BLUE 199
416-180-2
12222-04-7
Acute Tox. 4; STOT RE 2
218-961-1
2303-16-4
Carc. 2; Acute Tox. 4
PINOLENE
417-870-6
83648-84-4
Skin Irrit. 2; Skin Sens. 1
686-814-2
34363-01-4
Skin Irrit. 2; Skin Sens. 1
204-697-4
124-40-3
Flam. Liq. 1; Acute Tox. 4; Skin Corr. 1B
204-697-4
124-40-3
Flam. Gas 1; Press. Gas; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
205-575-3
142-96-1
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
203-921-8
111-92-2
Flam. Liq. 3; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Eye Dam. 1
DNOAI
408-190-0
7585-14-0
Pyr. Liq. 1; Skin Corr. 1B
205-017-9
131-18-0
Repr. 1B
CM 26-137
406-052-4
125078-60-6
Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
203-733-6
110-05-4
Org. Perox. E; Flam. Liq. 2; Muta. 2
233-689-3
10311-84-9
Acute Tox. 2; Acute Tox. 3
205-016-3
131-17-9
Acute Tox. 4
234-454-8
12004-35-2
Carc. 1A; STOT RE 1; Skin Sens. 1
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Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Sens. 1
GENIPLEX A
401-610-3
122012-52-6
Acute Tox. 4; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
422-670-7
150202-11-2
Repr. 2; Acute Tox. 3; STOT RE 2
240-973-0
16919-58-7
Acute Tox. 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
239-793-5
15699-18-0
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1
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74195-78-1
Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
231-786-5
7727-54-0
Ox. Sol. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
237-499-1
13820-41-2
Acute Tox. 3; Skin Irrit. 2; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
215-116-9
1303-28-2
Carc. 1A; Acute Tox. 3
215-481-4
1327-53-3
Carc. 1A; Acute Tox. 2; Skin Corr. 1B
206-373-8
333-41-5
Acute Tox. 4

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