EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

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Last updated 06 December 2023. Database contains 4658 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU_BA Directive 2000/54/EC
reaction mass of: 5-chloro-2-methyl-4-isothiazolin-3-one [EC no. 247-500-7]and 2-methyl-2H-isothiazol-3-one [EC no. 220-239-6] (3:1); reaction mass of: 5-chloro-2-methyl-4-isothiazolin-3-one [EC no. 247-500-7]and 2-methyl-4-isothiazolin-3-one [EC no. 220-239-6] (3:1)
611-341-5
55965-84-9
Acute Tox. 2; Acute Tox. 3; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1A
reaction mass of: 7,9,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diyl-prop-2-enoate; 7,7,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diyl-prop-2-enoate
MONO 442
412-260-6
52658-19-2
Eye Irrit. 2; Skin Sens. 1
reaction mass of: dodecanoic acid (35-40 %); poly(1-7)lactate esters of dodecanoic acid (60-65 %)
PRIAZUL LAUROYL LACTYLATE; PRICARE LAURYL LACTYLATE (1:1.5)
412-590-0
58856-63-6
Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
reaction mass of: methyl 3-((1E)-2-methylprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate; methyl 3-((1Z)-2-methylprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate (20:80)
435-450-0
5460-63-9
Skin Sens. 1
reaction mass of: pentasodium bis[6-anilino-3,5'-disulfonatonaphthalene-2-azobenzene-1,2'-diolato]cobaltate(III); tetrasodium [6-anilino-3,5'-disulfonatonaphthalene-2-azobenzene-1,2'-diolato][6-anilino-5'-sulfamoyl-3-sulfonatonaphthalene-2-azobenzene-1,2'-diolato]cobaltate(III); trisodium bis[6-anilino-5'-sulfamoyl-3-sulfonatonaphthalene-2-azobenzene-1,2'-diolato]cobaltate(III)
444-290-0
508202-43-5
Eye Dam. 1; Skin Sens. 1
R—2,3-epoxy-1-propanol
R-GLYCIDOL
404-660-4
57044-25-4
Self-react. C; Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
sec-butyl propionate
611-802-0
591-34-4
Flam. Liq. 3
sodium 4-chloro-1-hydroxybutane-1-sulfonate
BISULPHITE ADDUCT; GR59658A
406-190-5
54322-20-2
Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
strychnine
200-319-7
57-24-9
Acute Tox. 1; Acute Tox. 2
sulphamidic acid; sulphamic acid; sulfamic acid
226-218-8
5329-14-6
Eye Irrit. 2; Skin Irrit. 2
terbuthylazine (ISO); N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine
227-637-9
5915-41-3
Acute Tox. 4; STOT RE 2
tert-butyl acetate
208-760-7
540-88-5
Flam. Liq. 2
tert-butyl nitrite
208-757-0
540-80-7
Flam. Liq. 2; Acute Tox. 4
theophylline; 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
200-385-7
58-55-9
Repr. 1B
tin(II) methanesulphonate
STANNOUS METHANE SULPHONAT; STANNOUS METHANE SULPHONATE; TIN (II) METHANE SULPHONATE; TIN METHANE SULPHONATE; TIN METHANESULFONATE; TIN SALT FS; ZINN(II) METHANESULFONATE; ZINN(II)-METHANSULFONAT
401-640-7
53408-94-9
Skin Corr. 1B; Acute Tox. 4; Skin Sens. 1
tolclofos-methyl (ISO); O-(2,6-dichloro-p-tolyl)-O,O-dimethyl thiophosphate
260-515-3
57018-04-9
Skin Sens. 1B
toluidine sulphate (1:1)
208-741-3
540-25-0
Carc. 2; Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
toluidinium chloride
208-740-8
540-23-8
Carc. 2; Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
triadimenol (ISO); (1RS,2RS;1RS,2SR)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; α-tert-butyl-β-(4-chlorophenoxy)-1H-1,2,4-triazole-1-ethanol
259-537-6
55219-65-3
Repr. 1B; Lact.; Acute Tox. 4
trichlorfon (ISO); dimethyl 2,2,2-trichloro-1-hydroxyethylphosphonate
200-149-3
52-68-6
Acute Tox. 4; Skin Sens. 1
trichloroacetonitrile
208-885-7
545-06-2
Acute Tox. 3
trimethylopropane tri(3-aziridinylpropanoate); (TAZ)
257-765-0
52234-82-9
Muta. 2; Eye Dam. 1; Skin Sens. 1
trisodium nitrilotriacetate
225-768-6
5064-31-3
Carc. 2; Acute Tox. 4; Eye Irrit. 2
troclosene sodium, dihydrate
610-700-3
51580-86-0
Acute Tox. 4; Eye Irrit. 2; STOT SE 3
urethane (INN); ethyl carbamate
200-123-1
51-79-6
Carc. 1B
vanadyl pyrophosphate
BTN; VPO CATALYST
406-260-5
58834-75-6
Eye Irrit. 2; Skin Sens. 1
vinclozolin (ISO); N-3,5-dichlorophenyl-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione
256-599-6
50471-44-8
Carc. 2; Repr. 1B; Skin Sens. 1
α, α, α,4-tetrachlorotoluene; p-chlorobenzotrichloride
226-009-1
5216-25-1
Carc. 1B; Repr. 2; STOT RE 1; Acute Tox. 4; STOT SE 3; Skin Irrit. 2
(2-(aminomethyl)phenyl)acetylchloride hydrochloride
X-17-17
417-410-4
61807-67-8
Acute Tox. 4; Skin Corr. 1A; Skin Sens. 1
(2R)-2-amino-2-phenylacetamide
420-370-0
6485-67-2
Eye Irrit. 2; Skin Sens. 1
(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)diammonium bis(hydrogen sulphate)
265-294-7
64969-36-4
Carc. 1B; Acute Tox. 4
(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone
T 1569; T001569
423-290-4
66938-41-8
Muta. 2
(5-chloro-2-methoxy-4-methyl-3-pyridyl) (4,5,6-trimethoxy-o-tolyl)methanone; pyriofenone
692-456-8
688046-61-9
Carc. 2
(6β)-6,19-epoxyandrost-4-ene-3,17-dione
433-490-3
6563-83-3
Skin Sens. 1
(E)-but-2-ene
210-855-3
624-64-6
Flam. Gas 1; Press. Gas
(S)-α-hydroxy-3-phenoxy-benzeneacetonitrile
441-070-6
61826-76-4
Acute Tox. 3; Eye Dam. 1; Skin Sens. 1
(Z)-2-methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid
431-520-1
64485-90-1
Flam. Sol. 1; Carc. 2
1,1-dimethylpropyl 3,5,5-trimethylperoxyhexanoate
LUPEROX 570
431-610-9
68860-54-8
Org. Perox. D; Skin Sens. 1
1,10-phenanthroline
200-629-2
66-71-7
Acute Tox. 3
1,2,3,4,5,6-hexachlorcyclohexanes with the exception of those specified elsewhere in this Annex
210-168-9
608-73-1
Carc. 2; Acute Tox. 3; Acute Tox. 4
1,2,3,4-tetranitrocarbazole
-
6202-15-9
Expl. 1.1; Acute Tox. 4
1,2-benzenedicarboxylic acid, dihexyl ester, branched and linear
271-093-5
68515-50-4
Repr. 1B
1,2-benzenedicarboxylic acid; di-C7-11-branched and linear alkylesters
271-084-6
68515-42-4
Repr. 1B
1,2-diethoxyethane
211-076-1
629-14-1
Flam. Liq. 2; Repr. 1A; Eye Irrit. 2
1,2-dihydro-6-hydroxy-4-methyl-1-[3-(1-methylethoxy)propyl]-2-oxo-3-pyridinecarbonitrile
FAT 92'364/A
411-990-2
68612-94-2
Skin Sens. 1
1,3-dioxolane
211-463-5
646-06-0
Flam. Liq. 2
1-(1-naphthylmethyl)quinolinium chloride
CIB R634
406-220-7
65322-65-8
Carc. 2; Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
1-benzyl-5-ethoxyimidazolidine-2,4-dione
BEH; FC-05; FCO5; WMT 1155
417-340-4
65855-02-9
Acute Tox. 4
1-benzylimidazolidine-2,4-dione
T-5914 AND 501006025007
421-340-1
6777-05-5
Acute Tox. 4
1-chloro-1-nitropropane
209-990-0
600-25-9
Acute Tox. 4
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