EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

Last updated 27 May 2024. Database contains 4753 unique substances/entries.
Filter the list

425-260-6
244634-31-9
STOT RE 2; Eye Dam. 1; Skin Sens. 1
247-162-0
25646-77-9
Acute Tox. 3; STOT RE 2; Skin Sens. 1
E.M.A.
406-790-7
26116-56-3
Eye Dam. 1
244-445-0
21564-17-0
Acute Tox. 2; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
430-760-2
219861-18-4
Acute Tox. 4; Skin Sens. 1
PHENETHYLAMMONIUM SALT OF FOSFOMYCIN
418-570-8
25383-07-7
Repr. 2
L-2-CHLOROPROPIONIC ACID; L-2-CHLORPROPIONSÄURE
411-150-5
29617-66-1
Acute Tox. 4; Skin Corr. 1A
433-010-2
2135910-74-4
Acute Tox. 4; Skin Sens. 1
219-306-2
2407-94-5
Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
219-306-2
2407-94-5
Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
424-980-8
22288-41-1
Flam. Liq. 2; Org. Perox. D; Skin Irrit. 2; Skin Sens. 1
246-147-6
24307-26-4
Acute Tox. 4
247-830-1
26590-20-5
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
206-022-9
288-88-0
Repr. 2; Acute Tox. 4; Eye Irrit. 2
220-120-9
2634-33-5
Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
219-514-3
2451-62-9
Muta. 1B; Acute Tox. 3; STOT RE 2; Eye Dam. 1; Skin Sens. 1
yes
219-603-7
2475-45-8
Carc. 1B; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
425-450-9
294-90-6
Skin Corr. 1B; Acute Tox. 4
219-371-7
2425-79-8
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
429-370-5
220410-74-2
Acute Tox. 4
218-817-8
2243-62-1
Carc. 2
433-580-2
214353-17-0
Acute Tox. 4; Skin Corr. 1B
433-580-2
214353-17-0
Carc. 1B; Acute Tox. 4; Skin Corr. 1B
246-011-6
24083-03-2
Acute Tox. 4
GOLPANOL APC
412-740-5
25965-81-5
Acute Tox. 4; Skin Sens. 1
4-(4-ETHYLCYCLOHEXYL)-ACETOPHENON
426-460-6
260415-81-4
Skin Sens. 1
429-040-0
272460-97-6
Eye Dam. 1
ENS 119
402-680-8
26576-84-1
Acute Tox. 4
O-NITROBENZALDEHYDDIMETHYLACETAL
423-830-9
20627-73-0
Skin Sens. 1
SURFADONE LP-300 SURFACTANT
403-730-1
2687-96-9
Skin Corr. 1B; Skin Sens. 1
219-989-7
2592-95-2
Expl. 1.3
432-840-2
220926-97-6
Acute Tox. 4
221-070-0
2997-92-4
Acute Tox. 4; Skin Sens. 1
427-180-7
239446-62-9
Acute Tox. 4; Skin Sens. 1
219-799-4
2536-05-2
Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
426-850-6
2032-75-9
Flam. Liq. 3; Skin Corr. 1A; Acute Tox. 4; Skin Sens. 1
2,3-ISOPROPYLIDENE DIOXYPHENOL
400-900-7
22961-82-6
Eye Dam. 1
218-741-5
2223-82-7
Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
218-173-8
2062-98-8
yes
219-397-9
2431-50-7
Carc. 2; Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
-
240494-71-7
Acute Tox. 4; Acute Tox. 3; STOT SE 1; STOT RE 2
218-645-3
2210-79-9
Muta. 2; Skin Irrit. 2; Skin Sens. 1
246-690-9
25167-70-8
Flam. Liq. 2; Asp. Tox. 1; STOT SE 3
-
21436-97-5
Carc. 1B; Acute Tox. 3
218-256-9
2095-02-5
Acute Tox. 4; STOT RE 2; Eye Irrit. 2
424-870-1
27624-67-5
Expl. 1.1; Eye Dam. 1
218-255-3
2095-01-4
Acute Tox. 4; STOT RE 2; Eye Irrit. 2
AZOGELB
421-430-9
28365-08-4
Acute Tox. 4; STOT RE 2
DICHLORO-2,6 P.T.F.M.A.
416-430-0
24279-39-8
Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
247-384-8
25973-55-1
yes

Export search results to: