EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1

Active Implantable Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.

Last updated 19 April 2024. Database contains 4753 unique substances/entries.
Filter the list

A complex combination of hydrocarbons produced by the distillation of coal tar and boiling in the range of approximately 240°C to 280°C (464°F to 536°F). Composed primarily of acenaphthene, naphthalene and alkyl naphthalene.
292-605-3
90640-84-9
Carc. 1B
The high-boiling distillation fraction obtained from the high temperature carbonization of bituminous coal which is further refined to remove excess crystalline salts. It consists primarily of creosote oil with some of the normal polynuclear aromatic salts, which are components of coal tar distillates, removed. It is crystal free at approximately 5°C (41°F).
274-565-9
70321-79-8
Carc. 1B
The low-boiling distillation fraction obtained from the high temperature carbonization of bituminous coal, which is further refined to remove excess crystalline salts. It consists primarily of creosote oil with some of the normal polynuclear aromatic salts, which are components of coal tar distillate, removed. It is crystal free at approximately 38°C (100°F).
274-566-4
70321-80-1
Carc. 1B
208-622-6
535-89-7
Acute Tox. 2
224-030-0
4170-30-3
Flam. Liq. 2; Muta. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
231-720-5
7700-17-6
Acute Tox. 3
206-083-1
299-86-5
Acute Tox. 4
202-704-5
98-82-8
Flam. Liq. 3; Asp. Tox. 1; STOT SE 3
206-992-3
420-04-2
Carc. 2; Repr. 2; Acute Tox. 3; STOT RE 2; Skin Corr. 1; Skin Sens. 1; Eye Dam. 1
244-544-9
21725-46-2
Acute Tox. 4
620-377-0
13067-93-1
Acute Tox. 3; STOT SE 1; Acute Tox. 4; Eye Irrit. 2
220-130-3
2636-26-2
Acute Tox. 4
223-099-4
3734-95-0
Acute Tox. 2; Acute Tox. 3
CSDCA
419-150-7
113136-77-9
Acute Tox. 4
427-230-8
5571-36-8
Repr. 1B; STOT RE 2
431-730-1
4277-06-9
Skin Irrit. 2; Skin Sens. 1
203-806-2
110-82-7
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
201-604-9
85-42-7
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
yes
203-630-6
108-93-0
Acute Tox. 4; STOT SE 3; Skin Irrit. 2
203-631-1
108-94-1
Flam. Liq. 3; Acute Tox. 4
235-527-7
12262-58-7
Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
235-527-7
12262-58-7
Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
200-636-0
66-81-9
Muta. 2; Repr. 1B; Acute Tox. 2
221-319-3
3066-71-5
STOT SE 3; Skin Irrit. 2
203-629-0
108-91-8
Flam. Liq. 3; Repr. 2; Acute Tox. 4; Skin Corr. 1B
CHMMS; CHMS; DYNASYLAN 9407; Z-6187
402-140-1
17865-32-6
Skin Irrit. 2
220-279-4
2699-11-8
Org. Perox. C; Acute Tox. 4; Skin Corr. 1B
220-279-4
2699-11-8
Org. Perox. A; Skin Corr. 1B; Acute Tox. 4
VIOLIFF
401-620-8
87731-18-8
Skin Sens. 1
206-016-6
287-92-3
Flam. Liq. 2
227-964-7
6053-68-5
Eye Irrit. 2; STOT SE 3
204-435-9
120-92-3
Flam. Liq. 3; Eye Irrit. 2; Skin Irrit. 2
428-340-9
238088-70-5
Skin Irrit. 2
CHLOROFORMIATE DE CYCLOPENTYLE; CYCLOPENTYLCHLORFORMIAT
411-460-0
50715-28-1
Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1
200-847-8
75-19-4
Flam. Gas 1; Press. Gas
405-230-9
101205-02-1
Repr. 2
642-974-5
400882-07-7
Carc. 2; Skin Sens. 1A
269-855-7
68359-37-5
Acute Tox. 2; Acute Tox. 3
269-855-7
68359-37-5
Acute Tox. 2
236-049-1
13121-70-5
Acute Tox. 4
261-043-0
57966-95-7
Repr. 2; Acute Tox. 4; STOT RE 2; Skin Sens. 1
257-842-9
52315-07-8
Acute Tox. 4; STOT SE 3
257-842-9
52315-07-8
Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
619-020-1
94361-06-5
Repr. 1B; Acute Tox. 3; STOT RE 2
601-785-8
121552-61-2
Skin Sens. 1
274-050-9
69581-33-5
Acute Tox. 3; Acute Tox. 4
DEM
408-120-9
65197-96-8
Acute Tox. 4; Eye Dam. 1
218-827-2
2244-16-8
Skin Sens. 1
432-960-5
124655-09-0
Acute Tox. 4
204-828-5
127-20-8
Skin Irrit. 2; Eye Dam. 1

Export search results to: