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Result 1-6 of 6 for carcinogenity

Chemical legislation,REACH,CLP Full entry
EN
carcinogenicity  
carcinogenity   (Not recommended)
   
Definition A substance or a mixture of substances which induce cancer or increase its incidence. Substances which have induced benign and malignant tumours in well performed experimental studies on animals are considered also to be presumed or suspected human carcinogens unless there is strong evidence that the mechanism of tumour formation is not relevant for humans.


Chemical legislation,REACH,CLP Full entry
EN
carcinogen  
 
Definition A chemical substance or a mixture of chemical substances which induce cancer or increase its incidence.


Chemical legislation,REACH Full entry
EN
carcinogen category 1  
carcinogenic substance category 1  
   
Definition Substances known to be carcinogenic to man. There is sufficient evidence to establish a causal associationbetween human exposure to a substance and the development of cancer.


Chemical legislation Full entry
EN
carcinogen category 2  
   
carcinogenic substance category 2  
Definition Substances which should be regarded as if they are carcinogenic to man. There is sufficient evidence to provide a strong presumption that human exposure to a substance may result in the development of cancer, generally on the basis of appropriate long-term animal studies and other relevant information.


Chemical legislation Full entry
EN
carcinogen category 3  
   
carcinogenic substance category 3  
 
Definition Substances which cause concern for man owing to possible carcinogenic effects but in respect of which the available information is not adequate for making a satisfactory assessment. There is some evidence from appropriate animal studies, but this is insufficient to place the substance in Category 2.


Chemical legislation Full entry
EN
carcinogenic, mutagenic or toxic to reproduction  
   
CMR  
   
Definition Substances meeting the criteria for classification as carcinogenic, mutagenic or toxic for reproduction category 1 or 2, in accordance with Directive 67/548/EEC, are substances of very high concern2. They may be included in Annex XIV and by that made subject to authorisation requirement. CMRs may be non-threshold (i.e. it is not possible to define a Derived No-Effect Level (DNEL)) or threshold (i.e. it is possible to define a DNEL).