Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Adequacy of study:
other information

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 401
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes

Test animals

Species:
other: Rat, Sprague-Dawley strain

Administration / exposure

Vehicle:
other: Suspension in sterile water

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs:
other: Signs of toxicity related to dose levels: No clinical signs were observed during the course of the study. Body weight The mean weight gain in treated animals was normal when compared with strain data.
Gross pathology:
Effects on organs:
Red spots were reported on the lungs of one female (1/5).
This finding was frequently reported in laboratory rats,
relation to the treatment was unlikely.

No organ or tissue gross findings were seen at necropsy of
other animals.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU