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EC number: 478-080-5 | CAS number: 57043-35-3
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish:
A study was performed to assess the acute toxicity of the test material to rainbow trout (Oncorhynchus mykiss). The method followed that described in the OECD Guidelines for Testing of Chemicals (1992) No 203, "Fish, Acute Toxicity Test" referenced as Method C.1 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
The 96-Hour LC50 based on nominal test concentrations was 24 mg/l with 95% confidence limits of 18 - 32 mg/l. The No Observed Effect Concentration was 10 mg/l.
It was considered unnecessary and unrealistic to test at concentrations in excess of 100 mg/l.
Short-term toxicity to aquatic invertebrates (Daphnia Magna):
A study was performed to assess the acute toxicity of the test material to Daphnia magna. The method followed that described in the OECD Guidelines for Testing of Chemicals (April 2004) No 202, "Daphnia sp, Acute Immobilisation Test" referenced as Method C.2 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
The 48-Hour EC50 for the test material to Daphnia magna based on nominal test concentrations was 75 mg/l with 95% confidence limits of 56 - 100 mg/l. The No Observed Effect Concentration was 56 mg/l.
Toxicity to aquatic algae and cyanobacteria:
A study was performed to assess the effect of the test material on the growth of the green alga Scenedesmus subspicatus. The method followed that described in the OECD Guidelines for Testing of Chemicals (1984) No 201, "Alga, Growth Inhibition Test" referenced as
Method C.3 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
Exposure of Scenedesmus subspicatusto the test material gave an EbC50 (72 h) value of 18 mg/l; 95% confidence limits 17 - 20 mg/l and an ErC50 (0 - 72 h) value of 34 mg/l; 95% confidence limits 27 - 43 mg/l. The No Observed Effect Concentration was 6.25 mg/l.
Toxicity to microorganisms:
A study was performed to assess the effect of the test material on the respiration of activated sewage sludge. The method followed that described in the OECD Guidelines for Testing of Chemicals (1984) No 209 "Activated Sludge, Respiration Inhibition Test", EEC Commission Directive 87/302/EEC and US EPA Draft Ecological Effects Test Guidelines OPPTS 850.6800.
Following a preliminary range-finding test, activated sewage sludge was exposed to an aqueous solution of the test material at concentrations of 100, 180, 320, 560 and 1000 mg/l for a period of 3 hours at a temperature of 21°C with the addition of a synthetic sewage as a respiratory substrate. The rate of respiration was determined after 30 minutes and 3 hours contact time and compared to data for the control and a reference material, 3,5-dichlorophenol.
The effect of the test material on the respiration of activated sewage sludge gave a 3-Hour EC50 of 750 mg/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 180 mg/l. The reference material gave a 3-Hour EC50 value of 9.9 mg/l.
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