Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Method and study report not available.

Data source

Materials and methods

Principles of method if other than guideline:
Method not available
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(3,4-dimethoxyphenyl)-3-methylbutyronitrile
EC Number:
244-082-8
EC Name:
2-(3,4-dimethoxyphenyl)-3-methylbutyronitrile
Cas Number:
20850-49-1
Molecular formula:
C13H17NO2
IUPAC Name:
2-(3,4-dimethoxyphenyl)-3-methylbutanenitrile

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 175 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
LD50 in rat = 1175 mg/kg bw
After absorption of the substance into the body, it is not excluded the possibility that it can slowly release cyanide.