Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
secondary source
Title:
Environmental and Human Safety of Major Surfactants: Alcohol Ethoxylates and Alkylphenol Ethoxylates.
Author:
Talmage, S.S
Year:
1994
Bibliographic source:
The Soap and Detergent Association, Lewis Publishers, Boca Raton CRC, Boca Raton, Fla.

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method B.1 (Acute Toxicity (Oral))
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Reference substance name:
NPE9, NPE 10, NPE 20
IUPAC Name:
NPE9, NPE 10, NPE 20
Test material form:
not specified
Details on test material:
NPE9, NPE 10, NPE 20

Test animals

Species:
other: mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
4 290 mg/kg bw
Based on:
test mat.
Remarks on result:
other: mouse NPE9

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU