Registration Dossier
Registration Dossier
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EC number: 222-048-3 | CAS number: 3327-22-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
In-vitro mutagenicity tests conducted with (3-chloro-2-hydroxypropyl)trimethylammonium chloride have given a positive result (8 microbial mutagenicity tests, chromosome aberration study in human lymphocytes, liver unscheduled DNA synthesis assay (mostly in line with OECD 482 recommendations), gene mutation study in Chinese hamster ovary cells (mostly in line with OECD 476 recommendations). In the mouse micronucleus test in vivo, mutagenicity was not observed. [Source : European Union Risk Assessment Report for (3-Chloro-2-hydroxypropyl)trimethylammonium Chloride, 2008]
Endpoint Conclusion:
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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