Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 266-045-5 | CAS number: 65997-16-2 High-Alumina cement is a mixture of chemical substances produced by burning or sintering at high temperature (greater than 1200°C (2192°F)) raw materials which are predominantly calcium carbonate, aluminium oxide, silica, and iron oxide. The chemical substances which are manufactured are confined in a crystalline mass. This category includes all of the chemical substances specified below when they are intentionally manufactured in the production of high-alumina cement. The primary members of this category are CaAl2O4, Ca4Al2Fe2O10, Ca12Al14O33, and Ca2SiO4. Other compounds listed below may also be included in the combination with these primary substances.@CaAl4O7@Ca2Al2SiO7@CaAl12O19@Ca4Al6SO16@Ca3Al2O6.@Ca12Al14Cl@CaO@Ca12Al14F2@Ca3SiO5@Ca6Al4Fe2.@Ca2Fe2O5.
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16 March 2010 - 31 March 2010
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.1 (Acute Toxicity (Oral))
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Test type:
- acute toxic class method
- Limit test:
- yes
Test material
- Reference substance name:
- Cement, alumina, chemicals
- EC Number:
- 266-045-5
- EC Name:
- Cement, alumina, chemicals
- Cas Number:
- 65997-16-2
- Molecular formula:
- 3CaO.Al2O3.CaCO3.11H2O
- IUPAC Name:
- Cement, alumina, chemicals
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- olive oil
- Doses:
- 2000 mg/kg
- No. of animals per sex per dose:
- 6 female Sprague Dawley rats; single dose of 2000 mg/kg body weight
- Control animals:
- yes
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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