Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 February 2009 - 08 May 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study has been performed according to OECD and EC guidelines and according to GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: estimation method
- Partition coefficient type:
- octanol-water
Test material
- Details on test material:
- Substance type: dark purple waxy solid
- Physical state: solid
- Stability under storage conditions: stable
- Storage condition of test material: at room temperature in the dark
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficientopen allclose all
- Type:
- Pow
- Partition coefficient:
- > 980 000
- Temp.:
- 20 °C
- Remarks on result:
- other: no pH measurement available
- Type:
- log Pow
- Partition coefficient:
- > 6
- Temp.:
- 20 °C
- Remarks on result:
- other: no pH measurement available
- Details on results:
- The analysed concentration of the test substance in the n-octanol sample was 372 g/kg. It corresponded with a solubility of 489 g/l. The test was carried out at a 1:1 (w/w) ratio. The saturation factor of the sample was 1.3. The results were accepted since the maximum nominal concentration was applied and the n-octanol solubility of the test substance was significantly higher than its water solubility.
The Pow, calculated as the quotient of the n-octanol- and water solubility, is > 9.8 x 105. It corresponds with a log Pow value of > 6.0. The high value is representative for the test substance.
Applicant's summary and conclusion
- Conclusions:
- The estimation method was used for the determination of the Pow of Custom Red #3. The Pow and log Pow value of the test substance at 20°C are > 9.8 x 10^5 and > 6.0, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
