Registration Dossier
Registration Dossier
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EC number: 939-173-0 | CAS number: -
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study
Data source
Materials and methods
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- Cas Number:
- 208711-51-7
- Molecular formula:
- C9H9NO2
- IUPAC Name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- Reference substance name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- IUPAC Name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
Constituent 1
Constituent 2
Method
Species / strain
- Species / strain / cell type:
- other: sat TA 98, TA 100, TA 102, TA 1535, TA 1537
- Metabolic activation:
- with and without
- Metabolic activation system:
- Aroclor rat liver S9-mix
Results and discussion
Test resultsopen allclose all
- Species / strain:
- other: sat TA 98, TA 100, TA 102, TA 1535, TA 1537
- Metabolic activation:
- with
- Genotoxicity:
- positive
- Remarks:
- weak positive effect on strain TA 1537
- Species / strain:
- other: sat TA 98, TA 100, TA 102, TA 1535, TA 1537
- Metabolic activation:
- without
- Genotoxicity:
- negative
- Remarks on result:
- other: all strains/cell types tested
- Remarks:
- Migrated from field 'Test system'.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
positive with metabolic activation
negative without metabolic activation
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