Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.

REACH

(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol

EC number: 413-110-2 | CAS number: 135861-56-2

Life Cycle description
Uses advised against

Toxicological information

Endpoint summary

Administrative data

Key value for chemical safety assessment

Additional information

Short description of key information:
In vitro mutagenicity studies on bacteria (Ames test) and mammalian cells (mouse lymphoma L5178Y cells) and in vitro genotoxic studies (chromosomic aberration tests) did not revealed any positive effects with the test substance

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

In vitro mutagenicity studies on bacteria (Ames test) and mammalian cells (mouse lymphoma L5178Y cells) and in vitro genotoxic studies (chromosomic aberration tests) did not revealed any positive effects with the test substance. According to criteria of DSD and CLP, the substance should not be classified.

Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.