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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: well performed OECD study but without GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
6-amino-7-methoxy-1,2,3,4-tetrahydroquinoxaline-2,3-dione
EC Number:
615-027-9
Cas Number:
69904-10-5
Molecular formula:
C9H9N3O3
IUPAC Name:
6-amino-7-methoxy-1,2,3,4-tetrahydroquinoxaline-2,3-dione
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.31
Temp.:
23 °C
pH:
ca. 4.9

Applicant's summary and conclusion

Conclusions:
The Log Pow of the test substance is -0.31 at 23°C.
Executive summary:

The partition coefficient n-octanol/water was determiend according to OECD 107 with the shake flask method. 10, 20 and 40 ml of a stock solution in water saturated n-octanol was shaken with 20 ml water (in duplicate) at 23 °C and the concentration of the test substance was determiend by UV-vis-spectroscopy.