Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Safety data sheet of the supplier
Title:
Safety data sheet of the ketoamide
Author:
Merck
Year:
2009
Bibliographic source:
Safety data sheet of the supplier
Report date:
2009

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
Cas Number:
764667-65-4
Molecular formula:
C16H12F6N4O2
IUPAC Name:
1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione

Test animals / tissue source

Species:
other: bovine
Strain:
not specified

Test system

Vehicle:
not specified

Results and discussion

In vivo

Results
Remarks on result:
other: not irritating

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
not irritating