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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature.

Data source

Reference
Title:
Unnamed
Year:
1988

Materials and methods

Principles of method if other than guideline:
Method: other
GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
Thionyl dichloride
EC Number:
231-748-8
EC Name:
Thionyl dichloride
Cas Number:
7719-09-7
Molecular formula:
Cl2 O S
IUPAC Name:
thionyl dichloride
Details on test material:
TS-Freetext:
Thionyl chloride, CAS No. 7719-09-7; no further data

Method

Species / strain
Species / strain / cell type:
other: Salmonella typhimurium TA98, TA100, TA1535, TA1537
Metabolic activation:
with and without
Test concentrations with justification for top dose:
no data
Details on test system and experimental conditions:
IUCLID4 Type: Ames test

Results and discussion

Test results
Metabolic activation:
with and without
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
not specified
Remarks on result:
other: other: Salmonella typhimurium TA98, TA100, TA1535, TA1537
Remarks:
Migrated from field 'Test system'.

Applicant's summary and conclusion