Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002
Report date:
2002

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
Deviations:
not specified
GLP compliance:
yes
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-dichloro-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
EC Number:
230-437-4
EC Name:
2,6-dichloro-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
Cas Number:
7139-02-8
Molecular formula:
C16H20Cl2N6
IUPAC Name:
2,6-dichloro-4,8-dipiperidinopyrimido[5,4-d]pyrimidine

Test animals

Species:
rabbit
Strain:
New Zealand White
Sex:
male

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The dose tested during the experimentation period of fourteen days did, not cause any death or any type of cutaneous irritation visually detectable.