Registration Dossier
Registration Dossier
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EC number: 700-536-1 | CAS number: 25628-08-4
Endpoint summary
Administrative data
Description of key information
For the evaluation of the skin irritating properties of tetraethylammonium perfluorobutanesulfonate an artificial 3D-skin model test according to OECD TG 439 was used.
The assessment of the eye irritating properties of tetraethylammonium perfluorobutanesulfonate was tested using the Hen's egg chorioallantoic membrane (HET-CAM) test according to the ICCVAM Test Method Evaluation Report: Appendix G: ICCVAM Recommended Protocol for Future Studies Using the Hen's Egg Test-Chorionallantoic Membrane (HET-CAM) Test method, November 2006.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Tetraethylammonium perfluorobutanesulfonate was not irritating in the artificial 3D-skin model and slightly irritating in the HET-CAM test
Effects on eye irritation: irritating
Justification for classification or non-classification
Due to the results of the 3D-skin model evaluation a classification for skin irritation is not justified.
In the HET-CAM test tetraethylammonium perfluorobutanesulfonate was slightly irritating a classification as Xi, R36 (GHS: Cat. 2, H319 : Causes serious eye irritation) is proposed in the absence of in vivo data
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