Registration Dossier
Registration Dossier
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EC number: 700-536-1 | CAS number: 25628-08-4
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- other information
- Reliability:
- other: comprehensive hazard assessment on potassium perfluorobutane sulfonate; report by the Australian Government
- Rationale for reliability incl. deficiencies:
- other: secondary literature (review)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Exisiting Chemical Hazard Assessment Report - Potassium Perfluorobutane Sulfonate
- Author:
- Australian Government - Department of Health and Ageing NICNAS
- Year:
- 2 005
- Bibliographic source:
- National Industrial Chemicals Notification and Assessment Scheme - Sydney NSW 2001 - Australia
Materials and methods
- Objective of study:
- toxicokinetics
Test material
- Reference substance name:
- Potassium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonate
- EC Number:
- 249-616-3
- EC Name:
- Potassium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonate
- Cas Number:
- 29420-49-3
- IUPAC Name:
- potassium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): low bioaccumulation potential based on study results
- Executive summary:
PFBS (potassium perfluorobutane sulfonate) is rapidly excreted in animals (monkeys) by the kidneys with up to 87% excreted in the urine within 24 hours post dosing. No difference is observed between male and female animals
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