Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 448-050-6 | CAS number: 444065-11-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
AquaticShort-term L(E)C50 results are available for each of the three trophic levels.
Fish:Short-term toxicity to Cyprinus carpiowas investigated in an OECD TG 203 limit test (Bouwman, 2004) at a nominal test concentration of 100mg/L. No mortality or other adverse effects could be observed at the end of the exposure period and therefore, a precise LC50 value could not be calculated and it is considered to be >0.015 mg/L (mean measured concentration).
Invertebrates:An OECD TG 202 acute toxicity test toDaphnia magna(Bouwman, 2004) was performed at a nominal test concentration of 100mg/L. After 48 hours, no immobilisation or other adverse effects were reported, and therefore a precise EC50 could not be determined and it is considered to be >0.019 mg/L (mean measured concentration).
Algae:An OECD TG 201 algal growth inhibition test (Bouwman, 2004) was performed at a nominal test concentration of 100mg/L. No significant effects regarding biomass or growth rate were observed after 72 hours exposure to the test substance. Therefore, a precise EC50 value could not be determined and it is considered to be > 0.01 mg/L (average exposure concentration). This is considered as the most sensitive species based on the lowest measured exposure concentration over all three trophic levels.
Toxicity to microorganisms:The toxicity to microorganisms was tested on sewage micro-organisms by measuring the respiration rate under defined conditions in accordance to OECD Guideline 209. Under the conditions of the test, no inhibition of respiration was observed in either replicate with an EC50 >100 mg/L. The test substance is therefore considered to be not toxic to waste water bacteria at concentrations exceeding the limit of solubility.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
