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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: study equivalent to EU/OECD guideline.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1981

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
no
Test type:
acute toxic class method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chlorobenzamide
EC Number:
210-195-6
EC Name:
2-chlorobenzamide
Cas Number:
609-66-5
Molecular formula:
C7H6ClNO
IUPAC Name:
2-chlorobenzamide

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: acetone/oil 2/10
Doses:
50, 500, 1000, 1250, 1500, 1750, 2000 mg/kg
No. of animals per sex per dose:
10 male rats, 10 female rats , 20 female rats at dose 2000mg/kg
Control animals:
no

Results and discussion

Effect levelsopen allclose all
Sex:
male
Dose descriptor:
LD50
Effect level:
1 390 mg/kg bw
Sex:
female
Dose descriptor:
LD50
Effect level:
ca. 1 250 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information harmful if swallowed Criteria used for interpretation of results: EU